Trait
SNPs associated with Abnormality of the liver
23 genetic variants across 14 genes have been associated with Abnormality of the liver in published research. Key genes include AKNA, APOE, ERLIN1.
Associated variants23 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs28679728 | — | GWAS association (p=5.0e-73) | Major Consortium Study |
| rs10433937 | HSD17B13 | GWAS association (p=2.0e-69) | Major Consortium Study |
| rs2954021 | — | GWAS association (p=3.0e-47) | Major Consortium Study |
| rs6982502 | — | GWAS association (p=1.0e-43) | Major Consortium Study |
| rs1408579 | ERLIN1 | GWAS association (p=1.0e-39) | Major Consortium Study |
| rs7032795 | AKNA | GWAS association (p=2.0e-32) | Major Consortium Study |
| rs10733608 | — | GWAS association (p=5.0e-32) | Major Consortium Study |
| rs1260326 | GCKR | GWAS association (p=2.0e-26) | Major Consortium Study |
| rs4841132 | LOC157273 | GWAS association (p=3.0e-26) | Major Consortium Study |
| rs887829 | UGT1A1 | GWAS association (p=6.0e-24) | Major Consortium Study |
| rs2642438 | MTARC1 | GWAS association (p=7.0e-23) | Major Consortium Study |
| rs6742078 | UGT1A10 | GWAS association (p=1.0e-21) | Major Consortium Study |
| rs28929474 | SERPINA1 | GWAS association (p=5.0e-21) | Major Consortium Study |
| rs13130041 | — | GWAS association (p=7.0e-18) | Major Consortium Study |
| rs11607757 | — | GWAS association (p=9.0e-18) | Major Consortium Study |
| rs4246215 | FEN1 | GWAS association (p=4.0e-17) | Major Consortium Study |
| rs4782568 | — | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs769449 | APOE | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs112875651 | — | GWAS association (p=8.0e-13) | Major Consortium Study |
| rs340025 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs738409 | PNPLA3 | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs4918722 | GPAM | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs58542926 | TM6SF2 | GWAS association (p=2.0e-61) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.