Trait
SNPs associated with Hypercholesterolemia, family history
20 genetic variants across 9 genes have been associated with Hypercholesterolemia, family history in published research. Key genes include APOA5, APOE, CELSR2.
Associated variants20 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs73015024 | — | GWAS association (p=1.0e-34) | Major Consortium Study |
| rs138294113 | — | GWAS association (p=1.0e-29) | Major Consortium Study |
| rs1065853 | — | GWAS association (p=1.0e-28) | Major Consortium Study |
| rs142130958 | — | GWAS association (p=7.0e-25) | Major Consortium Study |
| rs2980888 | — | GWAS association (p=7.0e-22) | Major Consortium Study |
| rs2954038 | — | GWAS association (p=1.0e-19) | Major Consortium Study |
| rs2954017 | — | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs1260326 | GCKR | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs4075673 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs58542926 | TM6SF2 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs11591147 | PCSK9 | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs7528419 | CELSR2 | GWAS association (p=8.0e-33) | Major Consortium Study |
| rs55730499 | LPA | GWAS association (p=1.0e-19) | Major Consortium Study |
| rs964184 | APOA5 | GWAS association (p=7.0e-23) | Major Consortium Study |
| rs7412 | APOE | GWAS association (p=7.0e-36) | Major Consortium Study |
| rs10455872 | LPA | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs28601761 | — | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs739846 | SUGP1 | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs12740374 | CELSR2 | GWAS association (p=3.0e-33) | Major Consortium Study |
| rs541041 | LOC124905593 | GWAS association (p=1.0e-14) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.