Trait
SNPs associated with Hypogonadism
115 genetic variants across 23 genes have been associated with Hypogonadism in published research. Key genes include AKR1C4, AMMECR1, AR.
Associated variants115 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1799941 | SHBG | GWAS association (p=1.0e-136) | Major Consortium Study |
| rs112800586 | — | GWAS association (p=3.0e-119) | Major Consortium Study |
| rs111386834 | — | GWAS association (p=4.0e-96) | Major Consortium Study |
| rs10822160 | JMJD1C | GWAS association (p=1.0e-70) | Major Consortium Study |
| rs10761752 | JMJD1C | GWAS association (p=3.0e-55) | Major Consortium Study |
| rs2883091 | AMMECR1 | GWAS association (p=3.0e-45) | Major Consortium Study |
| rs10521528 | RTL9 | GWAS association (p=1.0e-38) | Major Consortium Study |
| rs56196860 | — | GWAS association (p=1.0e-36) | Major Consortium Study |
| rs1260326 | GCKR | GWAS association (p=4.0e-29) | Major Consortium Study |
| rs28929474 | SERPINA1 | GWAS association (p=1.0e-25) | Major Consortium Study |
| rs727428 | — | GWAS association (p=9.0e-23) | Major Consortium Study |
| rs738409 | PNPLA3 | GWAS association (p=6.0e-20) | Major Consortium Study |
| rs56332871 | — | GWAS association (p=3.0e-19) | Major Consortium Study |
| rs34666276 | — | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs28397663 | — | GWAS association (p=4.0e-15) | Major Consortium Study |
| rs8061590 | ATP2A1 | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs5918764 | AR | GWAS association (p=6.0e-14) | Major Consortium Study |
| rs8023580 | NR2F2-AS1 | GWAS association (p=9.0e-14) | Major Consortium Study |
| rs1553344333 | — | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs58528265 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs3976 | — | GWAS association (p=7.0e-13) | Major Consortium Study |
| rs9986829 | — | GWAS association (p=9.0e-13) | Major Consortium Study |
| rs11655056 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs62033405 | FTO | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs12150660 | SHBG | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs202200760 | NR2F6 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs4149056 | SLCO1B1 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs73632187 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs6479897 | JMJD1C | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs7052964 | OPHN1 | GWAS association (p=5.0e-11) | Major Consortium Study |
| rs7893850 | AKR1C4 | GWAS association (p=9.0e-11) | Major Consortium Study |
| rs10278686 | — | GWAS association (p=9.0e-11) | Major Consortium Study |
| rs151231052 | — | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs7190396 | FTO | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs6472995 | — | GWAS association (p=2.0e-10) | Major Consortium Study |
| rs1931537 | AR | GWAS association (p=3.0e-10) | Major Consortium Study |
| rs7474269 | — | GWAS association (p=4.0e-10) | Major Consortium Study |
| rs314272 | — | GWAS association (p=4.0e-10) | Major Consortium Study |
| rs189925784 | — | GWAS association (p=5.0e-10) | Major Consortium Study |
| rs2179580 | — | GWAS association (p=7.0e-10) | Major Consortium Study |
| rs1576625 | — | GWAS association (p=7.0e-10) | Major Consortium Study |
| rs221618 | LIN28B | GWAS association (p=9.0e-10) | Major Consortium Study |
| rs72800804 | — | GWAS association (p=1.0e-09) | Major Consortium Study |
| rs768853122 | — | GWAS association (p=1.0e-09) | Major Consortium Study |
| rs367635475 | — | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs11620783 | — | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs3106471 | — | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs12382538 | — | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs6650071 | — | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs2070863 | SERPINF2 | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs4300163 | — | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs4914305 | — | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs6612531 | — | GWAS association (p=4.0e-09) | Major Consortium Study |
| rs12012453 | — | GWAS association (p=4.0e-09) | Major Consortium Study |
| rs1482582 | — | GWAS association (p=5.0e-09) | Major Consortium Study |
| rs5918548 | — | GWAS association (p=5.0e-09) | Major Consortium Study |
| rs376407406 | — | GWAS association (p=5.0e-09) | Major Consortium Study |
| rs9724048 | — | GWAS association (p=6.0e-09) | Major Consortium Study |
| rs2213532 | ZC3H12B | GWAS association (p=6.0e-09) | Major Consortium Study |
| rs5918947 | ZC3H12B | GWAS association (p=6.0e-09) | Major Consortium Study |
| rs4294353 | — | GWAS association (p=6.0e-09) | Major Consortium Study |
| rs6650067 | — | GWAS association (p=7.0e-09) | Major Consortium Study |
| rs28827315 | FAAH2 | GWAS association (p=7.0e-09) | Major Consortium Study |
| rs6650080 | — | GWAS association (p=8.0e-09) | Major Consortium Study |
| rs5947422 | — | GWAS association (p=8.0e-09) | Major Consortium Study |
| rs4465134 | — | GWAS association (p=8.0e-09) | Major Consortium Study |
| rs5964780 | — | GWAS association (p=9.0e-09) | Major Consortium Study |
| rs5964867 | — | GWAS association (p=9.0e-09) | Major Consortium Study |
| rs10126703 | — | GWAS association (p=9.0e-09) | Major Consortium Study |
| rs10996471 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs6653214 | ZC3H12B | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs6989669 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs4244111 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs6521698 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs1569235711 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs5947413 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs4551525 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs79598313 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs3005544 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs3006225 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs7696472 | UGT2B15 | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs5918944 | ZC3H12B | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs4823182 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs5946788 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs386825345 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs201343244 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs768170 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs145466514 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs7175531 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs190543502 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs75563620 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs1574351 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs578210 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs10020067 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs5989014 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs6608444 | — | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs12391266 | — | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs9723538 | — | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs61912060 | — | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs5918938 | ZC3H12B | GWAS association (p=4.0e-08) | Major Consortium Study |
Showing the top 100 of 115 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.