Trait
SNPs associated with Iron Metabolism Disease
14 genetic variants across 7 genes have been associated with Iron Metabolism Disease in published research. Key genes include AGO2, JAK2, PNPLA3.
Associated variants14 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs181058325 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs80215559 | — | GWAS association (p=1.0e-23) | Major Consortium Study |
| rs77375493 | JAK2 | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs1045539487 | — | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs855791 | TMPRSS6 | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs569809555 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs190823084 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs189563348 | SERPINB11 | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs186155253 | U2AF1 | GWAS association (p=8.0e-12) | Major Consortium Study |
| rs2294915 | — | GWAS association (p=9.0e-12) | Major Consortium Study |
| rs536135107 | PUM2 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs738409 | PNPLA3 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs370909140 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs150338909 | AGO2 | GWAS association (p=3.0e-11) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.