Trait

SNPs associated with Nicotine Metabolite Ratio

18 genetic variants across 4 genes have been associated with Nicotine Metabolite Ratio in published research. Key genes include CYP2A6, CYP2A7, CYP2T1P.

Associated variants18 total

rsidGeneEffectEvidence
rs56113850CYP2A6GWAS association (p=6.0e-261)Meta-analysis
rs34638591TMPRSS11EGWAS association (p=1.0e-12)Meta-analysis
rs113029345GWAS association (p=1.0e-41)Large GWAS
rs76935404GWAS association (p=1.0e-25)Large GWAS
rs10425738GWAS association (p=1.0e-24)Large GWAS
rs11878604GWAS association (p=7.0e-24)Large GWAS
rs7247903GWAS association (p=1.0e-21)Large GWAS
rs2316205GWAS association (p=4.0e-14)Large GWAS
rs4079366CYP2A7GWAS association (p=8.0e-14)Large GWAS
rs73931391GWAS association (p=2.0e-12)Large GWAS
rs2545770GWAS association (p=4.0e-11)Large GWAS
rs185308415CYP2T1PGWAS association (p=3.0e-09)Large GWAS
rs76617915GWAS association (p=2.0e-08)Large GWAS
rs2045966GWAS association (p=3.0e-08)Large GWAS
rs7507400GWAS association (p=4.0e-08)Large GWAS
rs12459249GWAS association (p=1.0e-39)Small GWAS
rs111825958GWAS association (p=6.0e-26)Small GWAS
rs111645190GWAS association (p=1.0e-23)Small GWAS

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.

Nicotine Metabolite Ratio — SNPs & genetic associations — Gene Wizard