Trait
SNPs associated with Opioid Use Disorder
16 genetic variants across 8 genes have been associated with Opioid Use Disorder in published research. Key genes include FES, KCNN1, KDM4A.
Associated variants16 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs3778151 | OPRM1 | GWAS association (p=9.0e-11) | Meta-analysis |
| rs4702 | FES | GWAS association (p=3.0e-10) | Meta-analysis |
| rs7272308 | — | GWAS association (p=6.0e-09) | Meta-analysis |
| rs1415556 | LINC02661 | GWAS association (p=8.0e-09) | Meta-analysis |
| rs1831060692 | RABEPK | GWAS association (p=2.0e-08) | Meta-analysis |
| rs76450220 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs112068658 | KCNN1 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs4919566 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs6912701 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs1940701 | NCAM1 | GWAS association (p=4.0e-08) | Meta-analysis |
| rs1799971 | OPRM1 | GWAS association (p=3.0e-13) | Meta-analysis |
| rs540090452 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs3791033 | KDM4A | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs640561 | LOC105378801 | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs12931235 | — | GWAS association (p=7.0e-10) | Large GWAS |
| rs10014685 | — | GWAS association (p=2.0e-09) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.