Trait
SNPs associated with Optic Cup Area
62 genetic variants across 17 genes have been associated with Optic Cup Area in published research. Key genes include ATOH7, BCAS3, CDKN2B-AS1.
Associated variants62 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs7865618 | CDKN2B-AS1 | GWAS association (p=1.0e-21) | Meta-analysis |
| rs6054383 | — | GWAS association (p=4.0e-15) | Meta-analysis |
| rs11651885 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs1346 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs9546434 | DCLK1 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs3924048 | — | GWAS association (p=1.0e-10) | Meta-analysis |
| rs3858145 | — | GWAS association (p=4.0e-10) | Meta-analysis |
| rs10846617 | ZNF664-RFLNA | GWAS association (p=7.0e-10) | Meta-analysis |
| rs5756813 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs2113818 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs1402538 | — | GWAS association (p=4.0e-09) | Meta-analysis |
| rs301801 | — | GWAS association (p=5.0e-09) | Meta-analysis |
| rs10130556 | LOC105370504 | GWAS association (p=5.0e-09) | Meta-analysis |
| rs6764184 | FLNB | GWAS association (p=1.0e-08) | Meta-analysis |
| rs11247230 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs11870935 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs1346786 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs2623325 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs11646917 | — | GWAS association (p=5.0e-09) | Meta-analysis |
| rs1033667 | CHEK2 | GWAS association (p=1.0e-17) | Meta-analysis |
| rs10483727 | — | GWAS association (p=2.0e-27) | Meta-analysis |
| rs7972528 | — | GWAS association (p=3.0e-09) | Meta-analysis |
| rs1360589 | — | GWAS association (p=1.0e-31) | Large GWAS |
| rs4436712 | — | GWAS association (p=2.0e-29) | Large GWAS |
| rs6573308 | — | GWAS association (p=2.0e-24) | Large GWAS |
| rs738722 | CHEK2 | GWAS association (p=8.0e-22) | Large GWAS |
| rs2078555 | CHEK2 | GWAS association (p=2.0e-19) | Large GWAS |
| rs9546383 | — | GWAS association (p=5.0e-18) | Large GWAS |
| rs324775 | — | GWAS association (p=6.0e-17) | Large GWAS |
| rs6054375 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs12951741 | — | GWAS association (p=8.0e-16) | Large GWAS |
| rs7323428 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs7916697 | ATOH7 | GWAS association (p=9.0e-13) | Large GWAS |
| rs11613189 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs13016883 | TRIB2 | GWAS association (p=2.0e-11) | Large GWAS |
| rs1858610 | PLCE1 | GWAS association (p=5.0e-11) | Large GWAS |
| rs12494328 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs114537871 | — | GWAS association (p=8.0e-11) | Large GWAS |
| rs34222435 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs12789028 | LTBP3 | GWAS association (p=1.0e-10) | Large GWAS |
| rs4765352 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs2252865 | RERE | GWAS association (p=1.0e-09) | Large GWAS |
| rs2251069 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs1420993 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs2412973 | HORMAD2 | GWAS association (p=5.0e-09) | Large GWAS |
| rs117598310 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs6598351 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs6804624 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs35084382 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs1074407 | TRIOBP | GWAS association (p=2.0e-08) | Large GWAS |
| rs1343920 | LOC105370504 | GWAS association (p=2.0e-08) | Large GWAS |
| rs7101609 | FAT3 | GWAS association (p=2.0e-08) | Large GWAS |
| rs2684249 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs1622797 | LINC00917 | GWAS association (p=3.0e-08) | Large GWAS |
| rs1379096 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs4299136 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs12593656 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs3791679 | EFEMP1 | GWAS association (p=5.0e-08) | Large GWAS |
| rs4936099 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs10998036 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs482507 | — | GWAS association (p=6.0e-15) | Large GWAS |
| rs11867840 | BCAS3 | GWAS association (p=1.0e-13) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.