Trait
SNPs associated with Periodontitis
20 genetic variants across 9 genes have been associated with Periodontitis in published research. Key genes include AKAP6, FTO, GLT6D1.
Associated variants20 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs729876 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs11084095 | — | GWAS association (p=5.0e-08) | Meta-analysis |
| rs1800629 | TNF | Increased susceptibility to chronic and aggressive periodontitis | Meta-analysis |
| rs75933965 | TCF7L2 | GWAS association (p=6.0e-13) | Large GWAS |
| rs8047395 | FTO | GWAS association (p=2.0e-12) | Large GWAS |
| rs12255678 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs149290349 | ZFP36L2 | GWAS association (p=3.0e-10) | Large GWAS |
| rs10770140 | TH | GWAS association (p=8.0e-10) | Large GWAS |
| rs76895963 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs4376068 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs1537415 | GLT6D1 | GWAS association (p=6.0e-09) | Large GWAS |
| rs77464186 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs3200401 | MALAT1 | GWAS association (p=9.0e-09) | Large GWAS |
| rs17522122 | AKAP6 | GWAS association (p=1.0e-08) | Large GWAS |
| rs2010390 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs2546494 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs6711375 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs1265758 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs665268 | MLX | GWAS association (p=5.0e-08) | Large GWAS |
| rs242016 | — | GWAS association (p=2.0e-08) | Small GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.