Trait
SNPs associated with Splenomegaly
16 genetic variants across 11 genes have been associated with Splenomegaly in published research. Key genes include AFF3, ATXN2, CTNND2.
Associated variants16 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs3184504 | SH2B3 | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs597808 | ATXN2 | GWAS association (p=7.0e-16) | Major Consortium Study |
| rs570314267 | SRGAP1 | GWAS association (p=7.0e-14) | Major Consortium Study |
| rs561662177 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs141679963 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs373928778 | AFF3 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs142475842 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs185451453 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs73004951 | PBX4 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs145615167 | CTNND2 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs545337603 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs553147286 | PDE1C | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs544255576 | SGCZ | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs541207855 | SOX6 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs738409 | PNPLA3 | GWAS association (p=4.0e-23) | Major Consortium Study |
| rs77375493 | JAK2 | GWAS association (p=1.0e-100) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.