CD33
CD33 molecule
Summary
Enables protein phosphatase binding activity; protein tyrosine phosphatase activator activity; and sialic acid binding activity. Involved in several processes, including immune response-regulating signaling pathway; negative regulation of cytokine production; and negative regulation of monocyte activation. Located in Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants55 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs181266376 | 19:51,717,654 | A/C | downstream gene variant | — |
| rs1697573 | 19:51,718,317 | T/A | downstream gene variant | — |
| rs116623489 | 19:51,720,698 | C/T | intergenic variant | — |
| rs273640 | 19:51,725,824 | G/C | — | — |
| rs547724741 | 19:51,725,858 | T/A | — | — |
| rs3826656 | 19:51,726,613 | G/A | upstream gene variant | — |
| rs3865444 | 19:51,727,962 | A/C | upstream gene variant | — |
| rs2459141 | 19:51,728,193 | T/C | — | benign |
| rs1599865323 | 19:51,728,375 | A/G | — | uncertain significance |
| rs143114570 | 19:51,728,475 | G/A | — | benign |
| rs12459419 | 19:51,728,477 | C/T | missense variant | benign |
| rs201527883 | 19:51,728,512 | C/G | — | uncertain significance |
| rs771741922 | 19:51,728,545 | G/A | — | uncertain significance |
| rs61736469 | 19:51,728,567 | T/C | — | benign |
| rs145376903 | 19:51,728,587 | G/A | — | uncertain significance |
| rs780479679 | 19:51,728,600 | C/T | — | uncertain significance |
| rs529210091 | 19:51,728,617 | T/C | — | uncertain significance |
| rs144102805 | 19:51,728,621 | G/A | — | likely benign |
| rs115684563 | 19:51,728,629 | G/C | — | benign |
| rs2455069 | 19:51,728,641 | A/G | missense variant | benign |
| rs536711595 | 19:51,728,707 | C/T | — | uncertain significance |
| rs555362730 | 19:51,728,708 | G/A | missense variant | Likely benign |
| rs150563546 | 19:51,728,758 | G/A | — | uncertain significance |
| rs761220053 | 19:51,728,773 | A/G | — | uncertain significance |
| rs750670998 | 19:51,728,786 | T/A | — | uncertain significance |
| rs202143203 | 19:51,728,791 | C/T | — | uncertain significance |
| rs146181856 | 19:51,728,815 | T/C | — | likely benign |
| rs34919259 | 19:51,728,819 | G/A | — | benign |
| rs61736473 | 19:51,728,846 | A/G | — | benign |
| rs1450380687 | 19:51,729,062 | T/C | — | uncertain significance |
| rs376172530 | 19:51,729,095 | C/T | — | uncertain significance |
| rs571957160 | 19:51,729,105 | C/T | — | likely benign |
| rs2513961229 | 19:51,729,196 | T/A | — | uncertain significance |
| rs374361331 | 19:51,729,207 | C/G | — | likely benign |
| rs116187588 | 19:51,729,216 | T/C | — | benign |
| rs1274826359 | 19:51,729,239 | C/T | — | uncertain significance |
| rs11882250 | 19:51,729,594 | T/C | — | benign |
| rs142611321 | 19:51,731,027 | T/A | intron variant | — |
| rs7245846 | 19:51,731,176 | G/A | intron variant | — |
| rs187388451 | 19:51,733,974 | C/T | intron variant | — |
| rs141110039 | 19:51,737,039 | T/C | intron variant | — |
| rs149842697 | 19:51,737,089 | G/A | intron variant | — |
| rs138585047 | 19:51,737,794 | G/A | intron variant | — |
| rs1035783987 | 19:51,738,459 | G/C | — | uncertain significance |
| rs58981829 | 19:51,738,465 | G/A | — | benign |
| rs1981729322 | 19:51,738,863 | A/G | — | uncertain significance |
| rs201364242 | 19:51,738,905 | C/A | — | uncertain significance |
| rs35112940 | 19:51,738,917 | G/A | missense variant | benign |
| rs61736475 | 19:51,738,920 | T/C | — | benign |
| rs273621 | 19:51,738,933 | T/C | — | benign |
| rs10409348 | 19:51,739,226 | A/G | — | benign |
| rs146995981 | 19:51,739,227 | T/C | — | benign |
| rs148707213 | 19:51,739,400 | G/C | — | benign |
| rs147713159 | 19:51,742,833 | G/A | — | likely benign |
| rs1803254 | 19:51,743,144 | G/C | 3 prime UTR variant | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.