CLCN6

Cl-/H+ antiporter 6

Summary

This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012]

Known Variants724 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs3753584	1:11,864,586	T/C	regulatory region variant	—
rs13306561	1:11,865,804	A/G	regulatory region variant	—
rs13306560	1:11,866,183	C/T	regulatory region variant	benign
rs1010248218	1:11,866,323	G/A	—	uncertain significance
rs1319057021	1:11,866,326	G/A	—	uncertain significance
rs962654026	1:11,866,332	A/G	—	uncertain significance
rs1307720597	1:11,866,335	G/A	—	uncertain significance
rs780153104	1:11,866,336	G/A	—	uncertain significance
rs140859848	1:11,866,337	G/T	—	likely benign
rs755256371	1:11,866,339	C/T	—	uncertain significance
rs150143694	1:11,866,341	C/G	—	uncertain significance
rs771903854	1:11,866,343	G/A	—	likely benign
rs371115668	1:11,866,349	C/T	—	likely benign
rs77130610	1:11,866,357	G/A	—	uncertain significance
rs2523015203	1:11,866,368	T/A	—	uncertain significance
rs2100592946	1:11,866,373	C/T	—	likely benign
rs1644507807	1:11,866,375	G/C	—	uncertain significance
rs769631586	1:11,866,387	C/T	—	uncertain significance
rs767943876	1:11,866,389	C/T	—	uncertain significance
rs2100593041	1:11,866,392	A/C	—	uncertain significance
rs1168074088	1:11,866,393	C/T	—	uncertain significance
rs199831015	1:11,866,394	C/A	—	benign
rs945145964	1:11,866,397	C/G	—	likely benign
rs146516967	1:11,866,400	G/A	—	likely benign
rs1039380090	1:11,866,416	C/T	—	likely benign
rs753976878	1:11,866,419	C/A	—	likely benign
rs2523016405	1:11,866,423	G/C	—	likely benign
rs3737965	1:11,866,451	G/A	regulatory region variant	—
rs3737964	1:11,867,044	T/G	—	—
rs201666128	1:11,867,168	C/T	—	likely benign
rs369972988	1:11,867,171	C/T	—	likely benign
rs1417909302	1:11,867,174	A/G	—	likely benign
rs904450271	1:11,867,178	G/A	—	likely benign
rs7555034	1:11,867,180	T/G	—	benign
rs766813777	1:11,867,193	C/T	—	likely benign
rs2523023652	1:11,867,203	A/G	—	uncertain significance
rs1313842606	1:11,867,211	G/A	—	likely benign
rs143022405	1:11,867,214	G/A	—	likely benign
rs752842955	1:11,867,217	G/C	—	uncertain significance
rs377627467	1:11,867,220	T/G	—	uncertain significance
rs1644526951	1:11,867,230	C/A	—	uncertain significance
rs2523024111	1:11,867,239	G/T	—	uncertain significance
rs745834239	1:11,867,243	A/G	—	uncertain significance
rs755554098	1:11,867,250	G/A	—	uncertain significance
rs2100596167	1:11,867,261	A/T	—	likely benign
rs567502044	1:11,867,263	A/G	—	benign
rs1251882427	1:11,867,264	C/T	—	likely benign
rs1455953344	1:11,867,267	C/T	—	likely benign
rs564308517	1:11,870,180	A/T	—	—
rs17037427	1:11,873,416	A/T	—	—
rs1286657317	1:11,875,886	A/T	—	likely benign
rs2523067543	1:11,875,889	T/C	—	likely benign
rs767445795	1:11,875,892	C/G	—	likely benign
rs779413776	1:11,875,906	T/G	—	uncertain significance
rs1570519033	1:11,875,918	C/G	—	uncertain significance
rs1468963135	1:11,875,919	G/A	—	uncertain significance
rs1460591535	1:11,875,928	A/G	—	uncertain significance
rs1323312095	1:11,875,931	A/G	—	uncertain significance
rs1328054384	1:11,875,949	T/C	—	uncertain significance
rs781578347	1:11,875,953	G/A	—	likely benign
rs746358122	1:11,875,957	A/G	—	uncertain significance
rs2523068042	1:11,875,959	G/A	—	uncertain significance
rs146547070	1:11,875,979	C/A	—	benign
rs763027294	1:11,875,981	A/G	—	likely benign
rs1191928638	1:11,876,654	C/A	—	likely benign
rs17376328	1:11,876,662	G/A	intron variant	benign
rs1644675466	1:11,876,664	G/A	—	likely benign
rs762110634	1:11,876,673	A/G	—	uncertain significance
rs1314475259	1:11,876,674	A/G	—	likely benign
rs370967685	1:11,876,675	G/A	—	uncertain significance
rs1299044911	1:11,876,685	A/G	—	uncertain significance
rs200545314	1:11,876,686	T/C	—	benign
rs1010691032	1:11,876,691	C/T	—	uncertain significance
rs57044879	1:11,876,692	G/A	—	benign
rs1204139184	1:11,876,694	T/C	—	uncertain significance
rs2523071410	1:11,876,695	G/A	—	uncertain significance
rs764723407	1:11,876,704	G/A	—	uncertain significance
rs757917341	1:11,876,707	G/A	—	likely benign
rs780334882	1:11,876,718	T/C	—	uncertain significance
rs2523071573	1:11,876,721	G/T	—	uncertain significance
rs755598290	1:11,876,728	C/T	—	likely benign
rs1043645520	1:11,876,729	A/G	—	uncertain significance
rs1383030482	1:11,876,731	T/A	—	likely benign
rs1557780836	1:11,876,735	C/T	—	likely benign
rs2100616564	1:11,876,738	G/C	—	uncertain significance
rs779572789	1:11,876,746	G/A	—	likely benign
rs1644677151	1:11,876,751	G/A	—	likely benign
rs1321280097	1:11,876,752	C/G	—	likely benign
rs748169236	1:11,876,753	C/G	—	likely benign
rs2100621821	1:11,879,529	C/G	—	likely benign
rs1644714035	1:11,879,536	T/C	—	likely benign
rs747248779	1:11,879,542	C/A	—	uncertain significance
rs2523084178	1:11,879,545	G/T	—	likely benign
rs1644714393	1:11,879,548	G/T	—	uncertain significance
rs776926711	1:11,879,556	T/C	—	benign
rs1340556534	1:11,879,557	G/T	—	uncertain significance
rs745595684	1:11,879,562	C/T	—	likely benign
rs762928853	1:11,879,573	G/A	—	uncertain significance
rs953260141	1:11,879,582	C/A	—	uncertain significance
rs997317521	1:11,879,584	C/G	—	uncertain significance

Showing 100 of 724 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.