DENND4C

DENN domain containing 4C

Summary

Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to insulin stimulus; protein localization to plasma membrane; and regulation of Rab protein signal transduction. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants107 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs111654000	9:19,260,961	C/A	intron variant	—
rs12554932	9:19,261,301	G/A	intron variant	—
rs12554969	9:19,261,842	C/A	intron variant	—
rs12551960	9:19,267,440	C/A	—	—
rs41269019	9:19,290,794	A/C	—	uncertain significance
rs759430665	9:19,290,800	T/G	—	uncertain significance
rs184046911	9:19,290,805	G/C	—	uncertain significance
rs756932382	9:19,290,825	C/T	—	uncertain significance
rs745655243	9:19,296,025	A/G	—	uncertain significance
rs750723437	9:19,296,094	C/A	—	uncertain significance
rs2539551657	9:19,296,157	A/G	—	uncertain significance
rs201208731	9:19,296,211	C/G	—	uncertain significance
rs200121414	9:19,298,104	C/T	—	uncertain significance
rs2539605723	9:19,299,240	A/T	—	uncertain significance
rs1342614167	9:19,300,220	G/T	—	uncertain significance
rs754237209	9:19,300,234	G/T	—	uncertain significance
rs142917193	9:19,305,437	A/G	—	uncertain significance
rs770818546	9:19,305,475	C/A	—	uncertain significance
rs762458405	9:19,305,502	C/G	—	uncertain significance
rs150851153	9:19,305,521	T/C	—	uncertain significance
rs34150222	9:19,313,913	A/G	downstream gene variant	—
rs139309781	9:19,316,420	A/G	—	uncertain significance
rs1454893283	9:19,316,710	G/A	—	uncertain significance
rs2539852329	9:19,316,720	G/C	—	uncertain significance
rs2539852354	9:19,316,721	A/G	—	uncertain significance
rs1426619157	9:19,316,745	C/G	—	uncertain significance
rs745949702	9:19,324,405	T/G	—	uncertain significance
rs374351289	9:19,328,033	A/G	—	uncertain significance
rs766191608	9:19,328,072	C/T	—	uncertain significance
rs373619857	9:19,328,083	A/G	—	uncertain significance
rs749811218	9:19,328,108	C/T	—	uncertain significance
rs368083361	9:19,328,140	A/G	—	uncertain significance
rs1818218316	9:19,328,147	A/G	—	uncertain significance
rs908032020	9:19,331,986	C/G	—	uncertain significance
rs2540058359	9:19,332,043	T/A	—	uncertain significance
rs552385876	9:19,332,112	T/G	—	uncertain significance
rs142191750	9:19,332,140	A/C	—	likely benign
rs925421516	9:19,334,994	T/C	—	uncertain significance
rs2540114658	9:19,336,272	T/A	—	uncertain significance
rs746992252	9:19,336,304	A/C	—	uncertain significance
rs778656235	9:19,336,344	G/A	—	likely benign
rs35046772	9:19,336,407	T/C	—	uncertain significance
rs150173665	9:19,342,672	C/A	—	uncertain significance
rs2540198660	9:19,342,768	A/C	—	uncertain significance
rs760221882	9:19,342,772	G/A	—	uncertain significance
rs1224549082	9:19,346,033	T/C	—	uncertain significance
rs1822834766	9:19,346,128	A/G	—	uncertain significance
rs562059829	9:19,346,176	A/G	—	uncertain significance
rs145876383	9:19,346,197	G/T	—	uncertain significance
rs770932231	9:19,346,210	G/A	—	uncertain significance
rs138440750	9:19,346,335	C/T	—	uncertain significance
rs556426765	9:19,346,359	A/T	—	uncertain significance
rs142943763	9:19,346,377	A/G	—	uncertain significance
rs2540235768	9:19,346,402	G/T	—	uncertain significance
rs2540235997	9:19,346,419	A/G	—	uncertain significance
rs139571547	9:19,346,425	T/A	—	uncertain significance
rs2540236804	9:19,346,485	G/A	—	uncertain significance
rs149094194	9:19,346,501	A/G	—	uncertain significance
rs770807449	9:19,346,575	G/A	—	uncertain significance
rs2540239977	9:19,346,670	T/G	—	uncertain significance
rs140623138	9:19,346,726	A/G	—	uncertain significance
rs138264244	9:19,346,795	A/G	—	uncertain significance
rs954455713	9:19,346,810	C/T	—	uncertain significance
rs149625409	9:19,346,813	T/C	—	uncertain significance
rs1823004527	9:19,346,815	T/C	—	uncertain significance
rs144390071	9:19,346,825	A/C	—	uncertain significance
rs764145261	9:19,346,839	C/T	—	uncertain significance
rs975704287	9:19,346,864	G/A	—	uncertain significance
rs139483502	9:19,346,906	G/A	—	uncertain significance
rs768975276	9:19,347,048	A/G	—	likely benign
rs765129241	9:19,350,709	A/G	—	uncertain significance
rs764140442	9:19,350,718	T/C	—	uncertain significance
rs758662462	9:19,350,748	A/G	—	uncertain significance
rs145595726	9:19,350,792	G/C	—	uncertain significance
rs2540296504	9:19,350,817	A/C	—	uncertain significance
rs1823948485	9:19,350,820	A/C	—	uncertain significance
rs1823950367	9:19,350,825	T/A	—	uncertain significance
rs749453801	9:19,350,865	C/T	—	uncertain significance
rs2540297661	9:19,350,866	A/G	—	uncertain significance
rs762335258	9:19,352,082	T/C	—	uncertain significance
rs2540320550	9:19,352,172	G/A	—	uncertain significance
rs140547280	9:19,352,511	G/T	—	uncertain significance
rs143704727	9:19,352,548	A/G	—	uncertain significance
rs151075998	9:19,352,563	A/T	—	uncertain significance
rs762579335	9:19,357,134	G/C	—	uncertain significance
rs374436723	9:19,358,112	A/G	—	uncertain significance
rs200042865	9:19,358,118	T/G	—	uncertain significance
rs2540397109	9:19,358,159	G/A	—	uncertain significance
rs776165374	9:19,360,297	C/T	—	uncertain significance
rs1360366350	9:19,360,308	C/T	—	uncertain significance
rs1231926808	9:19,360,324	C/G	—	uncertain significance
rs752529201	9:19,360,371	A/G	—	uncertain significance
rs148640310	9:19,360,383	C/T	—	uncertain significance
rs769615203	9:19,360,386	A/G	—	uncertain significance
rs1397908967	9:19,360,390	T/C	—	uncertain significance
rs375445031	9:19,360,404	G/A	—	uncertain significance
rs75572195	9:19,360,566	G/A	intron variant	—
rs748923187	9:19,361,898	T/C	—	uncertain significance
rs746310674	9:19,361,959	T/G	—	uncertain significance
rs1254662485	9:19,369,853	C/T	—	uncertain significance

Showing 100 of 107 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.