GPR65
G protein-coupled receptor 65
Summary
Enables G protein-coupled receptor activity. Involved in several processes, including activation of GTPase activity; positive regulation of stress fiber assembly; and response to acidic pH. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants12 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs8005161 | 14:88,472,595 | C/T | regulatory region variant | — |
| rs746629867 | 14:88,477,278 | T/G | — | uncertain significance |
| rs139430517 | 14:88,477,307 | C/T | — | uncertain significance |
| rs749751887 | 14:88,477,516 | G/A | — | uncertain significance |
| rs1250920924 | 14:88,477,595 | G/A | — | uncertain significance |
| rs755703665 | 14:88,477,657 | G/A | — | uncertain significance |
| rs1335440037 | 14:88,477,687 | A/T | — | uncertain significance |
| rs765848791 | 14:88,477,771 | A/G | — | likely benign |
| rs1450703159 | 14:88,477,835 | C/T | — | uncertain significance |
| rs3742704 | 14:88,477,882 | A/C | missense variant | — |
| rs771833245 | 14:88,477,991 | G/A | — | likely benign |
| rs777862779 | 14:88,478,093 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.