HS6ST3
heparan sulfate 6-O-sulfotransferase 3
Summary
Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. These interactions are implicated in proliferation and differentiation, adhesion, migration, inflammation, blood coagulation, and other diverse processes (Habuchi et al., 2000 [PubMed 10644753]).[supplied by OMIM, Mar 2008]
Known Variants68 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs142119153 | 13:96,743,177 | A/C | — | uncertain significance |
| rs2053759061 | 13:96,743,241 | G/T | — | uncertain significance |
| rs375039520 | 13:96,743,247 | G/C | — | uncertain significance |
| rs146203986 | 13:96,743,249 | G/A | — | uncertain significance |
| rs750758063 | 13:96,743,265 | C/T | — | uncertain significance |
| rs2503411050 | 13:96,743,297 | C/A | — | uncertain significance |
| rs776259604 | 13:96,743,306 | G/A | — | uncertain significance |
| rs2053760282 | 13:96,743,336 | C/T | — | uncertain significance |
| rs1211171924 | 13:96,743,345 | G/C | — | uncertain significance |
| rs1202503369 | 13:96,743,354 | G/C | — | uncertain significance |
| rs2053760771 | 13:96,743,355 | A/C | — | uncertain significance |
| rs2503411227 | 13:96,743,356 | G/C | — | uncertain significance |
| rs1223921065 | 13:96,743,358 | G/T | — | uncertain significance |
| rs1449421544 | 13:96,743,361 | C/G | — | uncertain significance |
| rs1478518650 | 13:96,743,364 | G/A | — | uncertain significance |
| rs1206472409 | 13:96,743,445 | C/T | — | uncertain significance |
| rs755302154 | 13:96,743,520 | C/T | — | uncertain significance |
| rs1472337372 | 13:96,743,523 | G/A | — | uncertain significance |
| rs185615621 | 13:96,743,528 | G/A | — | uncertain significance |
| rs766926849 | 13:96,743,631 | A/G | — | uncertain significance |
| rs1376261301 | 13:96,743,649 | A/G | — | uncertain significance |
| rs1054334972 | 13:96,743,657 | C/G | — | uncertain significance |
| rs199763203 | 13:96,743,730 | G/A | — | uncertain significance |
| rs563195462 | 13:96,743,816 | C/T | — | uncertain significance |
| rs535812 | 13:96,765,619 | A/G | — | — |
| rs7318247 | 13:96,814,456 | G/C | — | — |
| rs117460454 | 13:96,815,074 | T/C | intron variant | — |
| rs75674569 | 13:96,823,724 | G/T | — | — |
| rs7331762 | 13:96,845,557 | T/C | intron variant | — |
| rs878950 | 13:96,854,681 | C/A | intron variant | — |
| rs9525149 | 13:96,855,782 | G/A | intron variant | — |
| rs764574 | 13:96,867,269 | C/A | — | — |
| rs78913805 | 13:96,875,910 | G/A | — | — |
| rs9525171 | 13:96,908,223 | C/G | intron variant | — |
| rs1927796 | 13:96,918,833 | A/T | — | — |
| rs1927790 | 13:96,922,191 | T/C | intron variant | — |
| rs2038823 | 13:96,951,433 | G/A | — | — |
| rs35092596 | 13:96,977,392 | T/A | — | — |
| rs1925113 | 13:96,977,695 | G/A | intron variant | — |
| rs7990098 | 13:96,982,541 | T/G | intron variant | — |
| rs7988861 | 13:96,982,624 | C/T | — | — |
| rs55911231 | 13:96,983,940 | C/T | — | — |
| rs61966940 | 13:96,993,465 | A/G | intron variant | — |
| rs4771935 | 13:96,996,902 | A/T | — | — |
| rs2892814 | 13:97,015,448 | T/A | — | — |
| rs7989336 | 13:97,017,548 | G/A | intron variant | — |
| rs7491529 | 13:97,020,634 | C/G | intron variant | — |
| rs912690 | 13:97,020,705 | C/G | intron variant | — |
| rs61967710 | 13:97,176,585 | G/A | intron variant | — |
| rs117226492 | 13:97,196,530 | G/A | intron variant | — |
| rs72642767 | 13:97,213,286 | A/T | intron variant | — |
| rs35253485 | 13:97,377,801 | A/G | intron variant | — |
| rs143612171 | 13:97,478,841 | G/C | intron variant | — |
| rs2501689487 | 13:97,484,905 | G/C | — | uncertain significance |
| rs142184149 | 13:97,484,933 | G/A | — | uncertain significance |
| rs1878833798 | 13:97,484,952 | G/A | — | uncertain significance |
| rs770895513 | 13:97,484,971 | G/A | — | uncertain significance |
| rs1244825117 | 13:97,485,011 | G/C | — | uncertain significance |
| rs139344619 | 13:97,485,170 | G/A | — | likely benign |
| rs377277765 | 13:97,485,217 | G/A | — | uncertain significance |
| rs777469390 | 13:97,485,222 | C/T | — | uncertain significance |
| rs753503506 | 13:97,485,223 | G/A | — | uncertain significance |
| rs764600252 | 13:97,485,294 | C/T | — | uncertain significance |
| rs140922305 | 13:97,485,295 | A/T | — | likely benign |
| rs374919031 | 13:97,485,327 | C/T | — | uncertain significance |
| rs778619413 | 13:97,485,328 | G/A | — | uncertain significance |
| rs2501690444 | 13:97,485,414 | G/A | — | uncertain significance |
| rs2501690510 | 13:97,485,447 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.