TAOK2

TAO kinase 2

Summary

Enables mitogen-activated protein kinase kinase binding activity; neuropilin binding activity; and protein serine/threonine kinase activity. Involved in several processes, including focal adhesion assembly; intracellular signal transduction; and positive regulation of MAPK cascade. Located in cytoplasmic vesicle; cytosol; and nuclear lumen. Part of receptor complex. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants631 total

rsidPosition (GRCh37)AllelesClassClinVar
rs1087145116:29,986,205C/T——
rs458325516:29,988,941A/Gdownstream gene variant—
rs75519929416:29,989,107G/T—uncertain significance
rs14611617916:29,989,109C/T—uncertain significance
rs124227222216:29,989,110G/C—uncertain significance
rs55433384616:29,989,114C/T—benign
rs75597270116:29,989,115G/A—uncertain significance
rs215088258616:29,989,116G/C—uncertain significance
rs134735548116:29,989,133G/A—uncertain significance
rs77041364316:29,989,138G/A—likely benign
rs76228076216:29,989,171G/T—uncertain significance
rs76338428616:29,989,180T/C—likely benign
rs75167050816:29,989,187C/T—uncertain significance
rs5635794216:29,989,216C/T—benign
rs126465295116:29,989,222C/T—likely benign
rs36868192516:29,989,237C/G—likely benign
rs77438205716:29,989,390C/T—likely benign
rs156723857816:29,989,392T/C—likely benign
rs130605154216:29,989,416G/A—uncertain significance
rs254360300816:29,989,428A/G—uncertain significance
rs20075319616:29,989,457C/T—likely benign
rs96646921716:29,989,477A/G—uncertain significance
rs93988634616:29,989,494C/T—likely benign
rs75804437816:29,989,499C/T—likely benign
rs77207255416:29,989,559C/T—likely benign
rs144654904016:29,989,566C/G—likely benign
rs206951573016:29,989,575A/G—likely benign
rs76176925616:29,989,601G/A—uncertain significance
rs15071210816:29,989,619G/A—likely benign
rs95718749516:29,989,626C/T—likely benign
rs75463783616:29,989,642C/T—uncertain significance
rs86579105016:29,989,643G/A—uncertain significance
rs6173795916:29,989,644G/A—benign
rs37392058816:29,989,653C/T—likely benign
rs120112311616:29,989,667C/T—uncertain significance
rs36806277916:29,989,668G/A—likely benign
rs254360784516:29,990,103C/T—likely benign
rs18857208116:29,990,109C/T—benign
rs206953314916:29,990,111C/G—likely benign
rs37591890316:29,990,114C/T—likely benign
rs254360795216:29,990,115C/T—likely benign
rs254360801216:29,990,127T/C—uncertain significance
rs128397950016:29,990,138C/G—uncertain significance
rs55798025816:29,990,143C/G—likely benign
rs119137761816:29,990,277T/G—likely benign
rs78048433016:29,990,282C/T—likely benign
rs75204607816:29,990,285C/G—likely benign
rs215088545616:29,990,287C/T—likely benign
rs206953961216:29,990,290T/C—likely benign
rs144324427316:29,990,292C/T—likely benign
rs138770666716:29,990,296G/A—likely benign
rs14948107116:29,990,338C/T—likely benign
rs37581364216:29,990,341C/T—likely benign
rs14436113316:29,990,353G/A—likely benign
rs254360949816:29,990,358T/G—uncertain significance
rs254360964316:29,990,388A/G—uncertain significance
rs75933884516:29,990,395C/A—uncertain significance
rs215088559816:29,990,397A/G—uncertain significance
rs20051792116:29,990,405C/T—likely benign
rs37700296416:29,990,406G/A—likely benign
rs206954553116:29,990,498G/A—likely benign
rs75633159916:29,990,501C/T—likely benign
rs74571512316:29,990,509C/T—likely benign
rs215088592816:29,990,510T/C—likely benign
rs57044301816:29,990,516G/A—uncertain significance
rs254361069616:29,990,529G/A—uncertain significance
rs134954569016:29,990,537C/T—likely benign
rs206954652216:29,990,543G/T—likely benign
rs254361079616:29,990,558A/T—uncertain significance
rs91957039116:29,990,560T/C—uncertain significance
rs254361085416:29,990,570G/A—likely benign
rs206954692616:29,990,584C/T—uncertain significance
rs20164822416:29,990,585G/A—likely benign
rs76808973016:29,990,589A/G—uncertain significance
rs93941798716:29,990,590T/A—uncertain significance
rs254361104716:29,990,600T/G—likely benign
rs14011794516:29,990,605A/G—uncertain significance
rs215088604216:29,990,608C/A—uncertain significance
rs76499369116:29,990,612C/T—likely benign
rs215088605716:29,990,613G/A—uncertain significance
rs77455236416:29,990,618C/T—likely benign
rs254361118616:29,990,628T/C—uncertain significance
rs76004777916:29,990,636G/A—uncertain significance
rs254361126016:29,990,640G/A—uncertain significance
rs53325757016:29,990,646T/C—likely benign
rs254361191216:29,990,722C/T—likely benign
rs254361192116:29,990,724G/T—likely benign
rs254361201816:29,990,742G/T—uncertain significance
rs37295156216:29,990,747C/T—likely benign
rs76795126616:29,990,748G/A—uncertain significance
rs148229981316:29,990,753G/A—likely benign
rs77601677816:29,990,762C/T—likely benign
rs127626841416:29,990,774G/A—likely benign
rs137768214516:29,990,781G/A—uncertain significance
rs37705603216:29,990,795C/T—likely benign
rs55412988216:29,990,798C/G—benign
rs147770600716:29,990,822C/T—likely benign
rs75488328616:29,990,847G/C—likely benign
rs78126162216:29,990,848T/C—likely benign
rs54114534716:29,992,962C/T—likely benign

Showing 100 of 631 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.