rs11731421
▶GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
body height
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.02
p 9.0e-43
N 394,642
Large GWAS
European
Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele A
OR 0.02
p 8.0e-36
N 405,540
Large GWAS
European
osteoarthritis, knee
Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)
Allele A
OR 1.05
p 2.0e-32
N 1,316,500
Large GWAS
multi-ancestry
Hollis B et al. “Lifetime risk and genetic predisposition to post-traumatic OA of the knee in the UK Biobank.” Osteoarthritis and Cartilage 31(10):1377-1387 (2023)
Allele A
OR 1.03
p 2.0e-8
N 354,561
Major Consortium StudyLarge GWAS
European
osteoarthritis, knee, total knee arthroplasty
Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)
Allele A
OR 1.09
p 2.0e-32
N 1,006,624
Large GWAS
multi-ancestry
osteoarthritis
Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)
Allele A
OR 1.03
p 5.0e-27
N 1,962,069
Large GWAS
multi-ancestry
osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty
Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)
Allele A
OR 1.06
p 2.0e-18
N 866,417
Large GWAS
multi-ancestry
BMI-adjusted hip circumference
Christakoudi S et al. “GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.” Scientific Reports 11(1):10688 (2021)
Allele A
OR 0.03
p 1.0e-15
N 186,825
Major Consortium StudyLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…