rs11772705

GWAS Catalog Trait Associations (11)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

hemoglobin measurement

Vuckovic D et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182(5):1214-1231.e11 (2020)
Allele C
OR 0.03
p 3.0e-29
N 408,112
Large GWAS
European
Allele C
OR 0.03
p 3.0e-14
N 172,925
Large GWAS
European
Allele C
OR 0.02
p 4.0e-8
N 153,950
Large GWAS
East Asian

low density lipoprotein cholesterol measurement

Allele C
OR 0.02
p 3.0e-15
N 394,642
Large GWAS
European
Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 6.0e-11
N 450,015
Large GWAS
multi-ancestry

total cholesterol measurement

Allele C
OR 0.02
p 3.0e-14
N 394,642
Large GWAS
European

free cholesterol in IDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 3.0e-13
N 450,015
Large GWAS
multi-ancestry

cholesterol in IDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 5.0e-13
N 450,015
Large GWAS
multi-ancestry

cholesterol to total lipids in small LDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 1.0e-12
N 450,015
Large GWAS
multi-ancestry

cholesteryl esters in IDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 1.0e-12
N 450,015
Large GWAS
multi-ancestry

free cholesterol in large LDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 2.0e-12
N 450,015
Large GWAS
multi-ancestry

total lipids in IDL

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 9.0e-12
N 450,015
Large GWAS
multi-ancestry

phospholipids in large LDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 3.0e-11
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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