Trait
SNPs associated with Cardiovascular Disease Risk
17 genetic variants across 7 genes have been associated with Cardiovascular Disease Risk in published research. Key genes include AP4B1, APOE, CDKN2B-AS1.
Associated variants17 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs429358 | APOE | Elevated LDL cholesterol | Meta-analysis |
| rs1894692 | — | GWAS association (p=7.0e-13) | Major Consortium Study |
| rs186696265 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs1906592 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs74617384 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs1333049 | CDKN2B-AS1 | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs145755371 | — | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs79712243 | LINC02196 | GWAS association (p=7.0e-12) | Major Consortium Study |
| rs140570886 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs114919961 | RAF1 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs181982343 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs7859727 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs2466455 | — | GWAS association (p=9.0e-09) | Large GWAS |
| rs10911021 | LOC105371642 | GWAS association (p=2.0e-08) | Large GWAS |
| rs10858023 | AP4B1 | GWAS association (p=3.0e-08) | Large GWAS |
| rs201654520 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs9923231 | VKORC1 | Increased cardiovascular disease risk | Preliminary work |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.