Trait
SNPs associated with Epilepsy
24 genetic variants across 9 genes have been associated with Epilepsy in published research. Key genes include AUTS2, BDNF, CHRM3.
Associated variants24 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs11890028 | SCN1A | GWAS association (p=8.0e-13) | Meta-analysis |
| rs59237858 | SCN1A | GWAS association (p=6.0e-12) | Meta-analysis |
| rs60055328 | SCN1A | GWAS association (p=3.0e-10) | Meta-analysis |
| rs6732655 | SCN1A | GWAS association (p=9.0e-10) | Meta-analysis |
| rs28498976 | — | GWAS association (p=5.0e-09) | Meta-analysis |
| rs1960242 | — | GWAS association (p=8.0e-09) | Meta-analysis |
| rs11978015 | — | GWAS association (p=9.0e-09) | Meta-analysis |
| rs4744696 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs28634186 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs6265 | BDNF | Increased epilepsy susceptibility | Meta-analysis |
| rs13032423 | — | GWAS association (p=9.0e-17) | Meta-analysis |
| rs3740422 | OGA | GWAS association (p=2.0e-12) | Meta-analysis |
| rs186028145 | AUTS2 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs73151649 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs6432877 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs13026414 | LOC101927235 | GWAS association (p=2.0e-09) | Large GWAS |
| rs4671319 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs72823592 | COPZ2 | GWAS association (p=9.0e-09) | Large GWAS |
| rs10496964 | — | GWAS association (p=9.0e-09) | Large GWAS |
| rs187977998 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs12059546 | CHRM3 | GWAS association (p=4.0e-08) | Large GWAS |
| rs998956939 | EXT1 | GWAS association (p=4.0e-08) | Large GWAS |
| rs4638568 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs12720071 | CNR1 | Increased risk of generalized Epilepsy | Candidate gene study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.