GLP2R
glucagon like peptide 2 receptor
Summary
This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014]
Known Variants44 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs757137217 | 17:9,729,391 | G/A | — | uncertain significance |
| rs2508131615 | 17:9,729,411 | G/A | — | uncertain significance |
| rs146116783 | 17:9,729,423 | G/A | — | uncertain significance |
| rs8072568 | 17:9,729,445 | A/T | — | benign |
| rs199595070 | 17:9,729,447 | G/A | — | uncertain significance |
| rs116054562 | 17:9,737,205 | C/G | — | benign |
| rs76930951 | 17:9,739,701 | C/T | — | benign |
| rs138494339 | 17:9,745,878 | C/T | — | uncertain significance |
| rs756008097 | 17:9,757,819 | G/A | — | likely benign |
| rs191831225 | 17:9,757,890 | C/G | — | uncertain significance |
| rs61730823 | 17:9,760,755 | G/A | — | benign |
| rs1439836471 | 17:9,760,799 | G/A | — | uncertain significance |
| rs141478969 | 17:9,760,817 | T/C | — | uncertain significance |
| rs139958183 | 17:9,760,825 | G/A | — | uncertain significance |
| rs61730821 | 17:9,760,892 | A/C | — | benign |
| rs142122440 | 17:9,763,274 | C/T | — | uncertain significance |
| rs114273181 | 17:9,763,386 | G/A | — | uncertain significance |
| rs763725104 | 17:9,764,494 | C/T | — | uncertain significance |
| rs1482651626 | 17:9,764,515 | G/A | — | uncertain significance |
| rs1361701890 | 17:9,765,367 | T/G | — | uncertain significance |
| rs200313014 | 17:9,774,124 | C/A | — | uncertain significance |
| rs564246878 | 17:9,774,129 | G/A | — | uncertain significance |
| rs9911768 | 17:9,779,769 | G/A | intron variant | — |
| rs7222481 | 17:9,785,187 | G/A | — | — |
| rs7222664 | 17:9,785,283 | G/C | intron variant | — |
| rs7223866 | 17:9,785,346 | C/A | — | — |
| rs17810376 | 17:9,787,845 | A/G | intron variant | — |
| rs7219033 | 17:9,787,958 | G/A | intron variant | — |
| rs17810412 | 17:9,788,279 | C/T | intron variant | — |
| rs77902029 | 17:9,791,780 | T/A | intron variant | — |
| rs368404871 | 17:9,792,718 | G/A | — | uncertain significance |
| rs748265296 | 17:9,792,732 | C/T | — | uncertain significance |
| rs143908746 | 17:9,792,733 | G/A | — | likely benign |
| rs17681684 | 17:9,792,768 | G/A | missense variant | — |
| rs61733939 | 17:9,792,774 | C/T | — | benign |
| rs775168959 | 17:9,792,775 | G/A | — | uncertain significance |
| rs777988807 | 17:9,792,843 | C/A | — | uncertain significance |
| rs112077837 | 17:9,792,903 | G/A | — | benign |
| rs778041025 | 17:9,792,925 | C/A | — | uncertain significance |
| rs16958918 | 17:9,792,928 | G/A | — | benign |
| rs148610687 | 17:9,792,937 | G/A | — | uncertain significance |
| rs371051147 | 17:9,792,957 | T/A | — | likely benign |
| rs55789050 | 17:9,793,417 | A/T | regulatory region variant | — |
| rs17743980 | 17:9,793,839 | G/C | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.