Trait
SNPs associated with concentration of large LDL particles measurement
89 genetic variants across 34 genes have been associated with concentration of large LDL particles measurement in published research. Key genes include ABCA6, ABCB11, ABCG5.
Associated variants89 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs7412 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs429358 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs12151108 | — | GWAS association (p=2.0e-288) | Large GWAS |
| rs12740374 | CELSR2 | GWAS association (p=3.0e-216) | Large GWAS |
| rs562338 | — | GWAS association (p=1.0e-201) | Large GWAS |
| rs118147862 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs1160983 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs693 | APOB | GWAS association (p=4.0e-88) | Large GWAS |
| rs58542926 | TM6SF2 | GWAS association (p=9.0e-86) | Large GWAS |
| rs12916 | HMGCR | GWAS association (p=3.0e-82) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=1.0e-75) | Large GWAS |
| rs28601761 | — | GWAS association (p=1.0e-67) | Large GWAS |
| rs35980001 | — | GWAS association (p=2.0e-64) | Large GWAS |
| rs12750160 | USP24 | GWAS association (p=2.0e-53) | Large GWAS |
| rs102274 | TMEM258 | GWAS association (p=2.0e-51) | Large GWAS |
| rs17205170 | LOC124901301 | GWAS association (p=5.0e-49) | Large GWAS |
| rs11887534 | ABCG5 | GWAS association (p=2.0e-44) | Large GWAS |
| rs58198139 | — | GWAS association (p=2.0e-42) | Large GWAS |
| rs7137828 | ATXN2 | GWAS association (p=1.0e-34) | Large GWAS |
| rs112875651 | — | GWAS association (p=2.0e-33) | Large GWAS |
| rs1168127 | DOCK7 | GWAS association (p=8.0e-33) | Large GWAS |
| rs12208357 | SLC22A1 | GWAS association (p=8.0e-32) | Large GWAS |
| rs624700 | USP1 | GWAS association (p=1.0e-29) | Large GWAS |
| rs3764261 | — | GWAS association (p=3.0e-28) | Large GWAS |
| rs147711004 | — | GWAS association (p=6.0e-28) | Large GWAS |
| rs1260326 | GCKR | GWAS association (p=4.0e-27) | Large GWAS |
| rs117310449 | — | GWAS association (p=5.0e-26) | Large GWAS |
| rs556107 | — | GWAS association (p=6.0e-26) | Large GWAS |
| rs34596921 | — | GWAS association (p=2.0e-25) | Large GWAS |
| rs6475606 | CDKN2B-AS1 | GWAS association (p=3.0e-25) | Large GWAS |
| rs56325564 | — | GWAS association (p=7.0e-25) | Large GWAS |
| rs6882345 | — | GWAS association (p=1.0e-24) | Large GWAS |
| rs2519093 | ABO | GWAS association (p=8.0e-24) | Large GWAS |
| rs115849089 | — | GWAS association (p=1.0e-22) | Large GWAS |
| rs4299376 | ABCG8 | GWAS association (p=2.0e-22) | Large GWAS |
| rs150169808 | — | GWAS association (p=8.0e-22) | Large GWAS |
| rs261290 | — | GWAS association (p=1.0e-21) | Large GWAS |
| rs76970536 | — | GWAS association (p=2.0e-21) | Large GWAS |
| rs1458038 | LOC124900725 | GWAS association (p=2.0e-19) | Large GWAS |
| rs77542162 | ABCA6 | GWAS association (p=2.0e-19) | Large GWAS |
| rs117113213 | — | GWAS association (p=5.0e-19) | Large GWAS |
| rs12150378 | — | GWAS association (p=6.0e-19) | Large GWAS |
| rs115478735 | ABO | GWAS association (p=9.0e-19) | Large GWAS |
| rs35081008 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs6602912 | — | GWAS association (p=1.0e-17) | Large GWAS |
| rs771193934 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs13702 | LPL | GWAS association (p=2.0e-17) | Large GWAS |
| rs72848251 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs174541 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs1883711 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs3794695 | — | GWAS association (p=6.0e-16) | Large GWAS |
| rs7734476 | CSNK1G3 | GWAS association (p=2.0e-15) | Large GWAS |
| rs633695 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs2738447 | LDLR | GWAS association (p=9.0e-15) | Large GWAS |
| rs2081687 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs516316 | FUT2 | GWAS association (p=2.0e-14) | Large GWAS |
| rs6940814 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs60403635 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs60517948 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs28550459 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs2287622 | ABCB11 | GWAS association (p=1.0e-13) | Large GWAS |
| rs116734477 | ITGA1 | GWAS association (p=3.0e-13) | Large GWAS |
| rs472495 | PCSK9 | GWAS association (p=4.0e-13) | Large GWAS |
| rs4307732 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs11621792 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs822928 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs11671606 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs4782568 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs6920309 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs11206517 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs3798167 | — | GWAS association (p=8.0e-12) | Large GWAS |
| rs34071855 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs41279633 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs17050272 | LOC105373585 | GWAS association (p=1.0e-11) | Large GWAS |
| rs7769410 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs247616 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs9837622 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs11693150 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs150474434 | INSIG2 | GWAS association (p=3.0e-11) | Large GWAS |
| rs1047891 | CPS1 | GWAS association (p=6.0e-11) | Large GWAS |
| rs11719254 | LOC107986092 | GWAS association (p=6.0e-11) | Large GWAS |
| rs9884390 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs2721953 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs59416866 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs62006566 | CSK | GWAS association (p=1.0e-10) | Large GWAS |
| rs72631343 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs1169289 | HNF1A | GWAS association (p=2.0e-10) | Large GWAS |
| rs61946991 | N4BP2L1 | GWAS association (p=4.0e-10) | Large GWAS |
| rs964184 | APOA5 | GWAS association (p=2.0e-86) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.