Trait
SNPs associated with rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement
43 genetic variants across 20 genes have been associated with rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement in published research. Key genes include ANKRD55, ATG5, CD40.
Associated variants43 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs6679677 | PHTF1 | GWAS association (p=4.0e-161) | Large GWAS |
| rs2476601 | PTPN22 | GWAS association (p=1.0e-160) | Large GWAS |
| rs34536443 | TYK2 | GWAS association (p=3.0e-27) | Large GWAS |
| rs7731626 | ANKRD55 | GWAS association (p=1.0e-26) | Large GWAS |
| rs11571297 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs3093017 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs11636401 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs897628 | TTC34 | GWAS association (p=3.0e-16) | Large GWAS |
| rs35926684 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs10517086 | LINC02357 | GWAS association (p=6.0e-16) | Large GWAS |
| rs3184504 | SH2B3 | GWAS association (p=8.0e-16) | Large GWAS |
| rs4853458 | STAT4 | GWAS association (p=5.0e-14) | Large GWAS |
| rs11889341 | STAT4 | GWAS association (p=5.0e-14) | Large GWAS |
| rs1538981 | — | GWAS association (p=8.0e-14) | Large GWAS |
| rs35942002 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs2451258 | LOC112267968 | GWAS association (p=2.0e-12) | Large GWAS |
| rs7117261 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs3757387 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs7749323 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs8129030 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs706778 | IL2RA | GWAS association (p=1.0e-11) | Large GWAS |
| rs2004640 | IRF5 | GWAS association (p=1.0e-11) | Large GWAS |
| rs35018800 | TYK2 | GWAS association (p=1.0e-11) | Large GWAS |
| rs7170107 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs9939427 | LOC124903741 | GWAS association (p=5.0e-11) | Large GWAS |
| rs76428106 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs72836346 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs73013527 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs8002731 | COG6 | GWAS association (p=4.0e-10) | Large GWAS |
| rs67574266 | — | GWAS association (p=6.0e-10) | Large GWAS |
| rs1471293 | — | GWAS association (p=7.0e-10) | Large GWAS |
| rs5987194 | MECP2 | GWAS association (p=8.0e-10) | Large GWAS |
| rs62045818 | — | GWAS association (p=9.0e-10) | Large GWAS |
| rs2409780 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs140675301 | STAT4 | GWAS association (p=2.0e-09) | Large GWAS |
| rs12720356 | TYK2 | GWAS association (p=2.0e-09) | Large GWAS |
| rs7278257 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs11558819 | ICOSLG | GWAS association (p=2.0e-09) | Large GWAS |
| rs1883832 | CD40 | GWAS association (p=1.0e-08) | Large GWAS |
| rs9427397 | FCGR2A | GWAS association (p=2.0e-08) | Large GWAS |
| rs2258734 | TNFRSF14 | GWAS association (p=3.0e-08) | Large GWAS |
| rs62422878 | ATG5 | GWAS association (p=4.0e-08) | Large GWAS |
| rs1950897 | RAD51B | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.