PLTP
phospholipid transfer protein
Summary
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Known Variants121 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2515452033 | 20:44,527,604 | G/A | — | likely benign |
| rs34881646 | 20:44,527,616 | C/T | — | likely benign |
| rs2145826459 | 20:44,527,629 | G/C | — | uncertain significance |
| rs147664819 | 20:44,527,647 | A/G | — | uncertain significance |
| rs2515452534 | 20:44,527,720 | G/C | — | likely benign |
| rs2515453628 | 20:44,528,106 | G/A | — | uncertain significance |
| rs896207883 | 20:44,528,110 | C/T | — | likely benign |
| rs139710284 | 20:44,528,116 | C/G | — | benign |
| rs766917794 | 20:44,528,117 | A/G | — | uncertain significance |
| rs372280032 | 20:44,528,126 | A/C | — | uncertain significance |
| rs752972129 | 20:44,528,153 | A/T | — | uncertain significance |
| rs745707576 | 20:44,528,165 | C/T | — | uncertain significance |
| rs1300743698 | 20:44,528,177 | T/G | — | uncertain significance |
| rs370035568 | 20:44,528,184 | G/T | — | likely benign |
| rs145642115 | 20:44,528,279 | C/T | — | uncertain significance |
| rs760077699 | 20:44,528,284 | A/G | — | uncertain significance |
| rs767960442 | 20:44,528,299 | T/A | — | uncertain significance |
| rs1455944943 | 20:44,528,318 | G/T | — | uncertain significance |
| rs764362720 | 20:44,528,328 | G/C | — | likely benign |
| rs1173679344 | 20:44,528,332 | G/A | — | likely benign |
| rs190186546 | 20:44,528,342 | G/A | — | benign |
| rs754757208 | 20:44,528,455 | A/C | — | likely benign |
| rs2515455410 | 20:44,528,470 | C/A | — | uncertain significance |
| rs1472662668 | 20:44,528,479 | A/T | — | uncertain significance |
| rs1227580210 | 20:44,528,517 | C/G | — | uncertain significance |
| rs778463054 | 20:44,528,521 | C/T | — | likely benign |
| rs778571774 | 20:44,530,896 | G/A | — | likely benign |
| rs11569652 | 20:44,530,900 | G/C | — | benign |
| rs144099277 | 20:44,530,908 | G/A | — | likely benign |
| rs368810601 | 20:44,530,910 | G/A | — | uncertain significance |
| rs146500616 | 20:44,530,923 | C/T | — | likely benign |
| rs1345212854 | 20:44,530,937 | T/C | — | uncertain significance |
| rs373043557 | 20:44,530,942 | C/T | — | uncertain significance |
| rs6065903 | 20:44,530,943 | G/A | — | benign |
| rs753786509 | 20:44,530,944 | G/A | — | likely benign |
| rs144710772 | 20:44,530,966 | C/T | — | uncertain significance |
| rs148188588 | 20:44,530,967 | G/A | — | uncertain significance |
| rs571813453 | 20:44,530,970 | C/T | — | uncertain significance |
| rs193100095 | 20:44,531,063 | A/T | — | likely benign |
| rs376766817 | 20:44,531,074 | C/T | — | uncertain significance |
| rs2515460165 | 20:44,531,127 | G/A | — | likely benign |
| rs2083196357 | 20:44,531,135 | T/A | — | uncertain significance |
| rs11569651 | 20:44,531,139 | G/A | — | benign |
| rs377317376 | 20:44,531,152 | G/A | — | uncertain significance |
| rs2515460246 | 20:44,531,155 | A/C | — | uncertain significance |
| rs577684935 | 20:44,531,170 | G/A | — | uncertain significance |
| rs752967608 | 20:44,531,199 | G/A | — | likely benign |
| rs200022812 | 20:44,531,203 | C/T | — | uncertain significance |
| rs373772930 | 20:44,531,218 | A/G | — | uncertain significance |
| rs368148295 | 20:44,533,427 | G/A | — | likely benign |
| rs199855701 | 20:44,533,440 | A/G | — | uncertain significance |
| rs762195629 | 20:44,533,470 | C/T | — | uncertain significance |
| rs138504134 | 20:44,533,474 | G/A | — | benign |
| rs143905045 | 20:44,533,490 | G/A | — | benign |
| rs540548008 | 20:44,533,582 | T/C | — | likely benign |
| rs147279890 | 20:44,533,584 | G/C | — | uncertain significance |
| rs1476211354 | 20:44,533,592 | C/T | — | uncertain significance |
| rs2083225625 | 20:44,533,613 | C/T | — | uncertain significance |
| rs61731059 | 20:44,533,614 | C/T | — | likely benign |
| rs142277281 | 20:44,533,615 | G/A | — | uncertain significance |
| rs56126980 | 20:44,533,618 | C/T | — | likely benign |
| rs139197557 | 20:44,533,631 | C/G | — | uncertain significance |
| rs2145835340 | 20:44,533,666 | A/T | — | uncertain significance |
| rs749649631 | 20:44,533,699 | G/A | — | uncertain significance |
| rs367756234 | 20:44,533,711 | C/T | — | uncertain significance |
| rs2083227010 | 20:44,533,713 | G/C | — | uncertain significance |
| rs1305303563 | 20:44,533,718 | G/A | — | uncertain significance |
| rs141035863 | 20:44,533,731 | C/T | — | likely benign |
| rs1353540801 | 20:44,533,738 | G/T | — | uncertain significance |
| rs6065904 | 20:44,534,651 | G/A | regulatory region variant | — |
| rs2145836768 | 20:44,534,932 | G/C | — | uncertain significance |
| rs370983158 | 20:44,534,981 | C/G | — | uncertain significance |
| rs747026724 | 20:44,534,982 | G/A | — | likely benign |
| rs775414533 | 20:44,534,996 | G/A | — | uncertain significance |
| rs370521313 | 20:44,536,314 | A/G | — | benign |
| rs771853701 | 20:44,536,317 | C/T | — | likely benign |
| rs143448263 | 20:44,536,333 | G/C | — | uncertain significance |
| rs1381038199 | 20:44,536,341 | G/C | — | uncertain significance |
| rs558168284 | 20:44,536,365 | C/T | — | likely benign |
| rs376779317 | 20:44,536,366 | G/A | — | uncertain significance |
| rs2229452 | 20:44,536,383 | G/A | — | benign |
| rs2515469808 | 20:44,536,387 | G/C | — | uncertain significance |
| rs200290139 | 20:44,536,460 | C/T | — | benign |
| rs138461220 | 20:44,536,492 | G/A | — | likely benign |
| rs940964022 | 20:44,536,494 | G/A | — | uncertain significance |
| rs375722812 | 20:44,536,500 | G/A | — | uncertain significance |
| rs1315617401 | 20:44,536,539 | C/A | — | uncertain significance |
| rs559294797 | 20:44,538,175 | C/T | — | likely benign |
| rs750514361 | 20:44,538,176 | G/A | — | uncertain significance |
| rs144016582 | 20:44,538,177 | C/T | — | uncertain significance |
| rs547730936 | 20:44,538,178 | G/A | — | likely benign |
| rs757314282 | 20:44,538,201 | G/C | — | uncertain significance |
| rs143020139 | 20:44,538,235 | G/A | — | likely benign |
| rs200777651 | 20:44,538,242 | C/T | — | likely benign |
| rs138807551 | 20:44,538,243 | G/A | — | uncertain significance |
| rs370451864 | 20:44,538,245 | G/C | — | uncertain significance |
| rs759898261 | 20:44,538,250 | C/T | — | likely benign |
| rs11569636 | 20:44,538,269 | G/T | — | benign |
| rs11544244 | 20:44,538,271 | C/T | — | benign |
| rs751031120 | 20:44,538,285 | A/C | — | uncertain significance |
Showing 100 of 121 variants. Use the SNP search for the full list.
Gene information from NCBI Gene. Variant classifications from ClinVar.