Trait
SNPs associated with Alcohol dependence
16 genetic variants across 6 genes have been associated with Alcohol dependence in published research. Key genes include ADH1B, ADH1C, CNR1.
Associated variants16 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1229984 | ADH1B | GWAS association (p=1.0e-45) | Meta-analysis |
| rs13135092 | — | GWAS association (p=5.0e-15) | Meta-analysis |
| rs11733695 | — | GWAS association (p=8.0e-13) | Meta-analysis |
| rs146788033 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs11940694 | KLB | GWAS association (p=1.0e-09) | Meta-analysis |
| rs2066702 | ADH1B | GWAS association (p=4.0e-11) | Large GWAS |
| rs1437396 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs149212747 | — | GWAS association (p=6.0e-10) | Large GWAS |
| rs1789882 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs1693457 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs904092 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs698 | ADH1C | Increased alcohol dependence risk | Large GWAS |
| rs7590720 | MREG | GWAS association (p=1.0e-08) | Large GWAS |
| rs1789891 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs4478858 | SERINC2 | GWAS association (p=3.0e-08) | Large GWAS |
| rs806368 | CNR1 | Increased risk via haplotype interaction | Candidate gene study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.