Trait
SNPs associated with complement C4 measurement
101 genetic variants across 24 genes have been associated with complement C4 measurement in published research. Key genes include AGER, BTNL2, C4B.
Associated variants101 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs424232 | — | GWAS association (p=1.0e-300) | Large GWAS |
| rs3130321 | TSBP1-AS1 | GWAS association (p=1.0e-300) | Large GWAS |
| rs2524084 | — | GWAS association (p=1.0e-300) | Large GWAS |
| rs2844495 | — | GWAS association (p=1.0e-300) | Large GWAS |
| rs3117579 | CSNK2B | GWAS association (p=1.0e-300) | Large GWAS |
| rs2284179 | — | GWAS association (p=1.0e-261) | Large GWAS |
| rs406658 | C4B | GWAS association (p=4.0e-218) | Large GWAS |
| rs10046127 | TNXB | GWAS association (p=4.0e-217) | Large GWAS |
| rs35795092 | AGER | GWAS association (p=5.0e-189) | Large GWAS |
| rs9469058 | — | GWAS association (p=5.0e-183) | Large GWAS |
| rs113720465 | CYP21A2 | GWAS association (p=9.0e-183) | Large GWAS |
| rs9296004 | SKIC2 | GWAS association (p=3.0e-180) | Large GWAS |
| rs57740770 | — | GWAS association (p=2.0e-157) | Large GWAS |
| rs2535300 | — | GWAS association (p=4.0e-145) | Large GWAS |
| rs11751198 | — | GWAS association (p=8.0e-145) | Large GWAS |
| rs41315816 | — | GWAS association (p=8.0e-140) | Large GWAS |
| rs534990050 | — | GWAS association (p=6.0e-138) | Large GWAS |
| rs915894 | NOTCH4 | GWAS association (p=6.0e-132) | Large GWAS |
| rs114212545 | — | GWAS association (p=2.0e-119) | Large GWAS |
| rs2075799 | HSPA1L | GWAS association (p=6.0e-97) | Large GWAS |
| rs3130486 | MSH5 | GWAS association (p=3.0e-94) | Large GWAS |
| rs707920 | — | GWAS association (p=5.0e-93) | Large GWAS |
| rs9394078 | — | GWAS association (p=3.0e-89) | Large GWAS |
| rs241428 | TAP2 | GWAS association (p=9.0e-83) | Large GWAS |
| rs61229539 | — | GWAS association (p=2.0e-80) | Large GWAS |
| rs2071278 | NOTCH4 | GWAS association (p=4.0e-72) | Large GWAS |
| rs3763317 | BTNL2 | GWAS association (p=9.0e-66) | Large GWAS |
| rs2607013 | — | GWAS association (p=2.0e-63) | Large GWAS |
| rs138565013 | — | GWAS association (p=2.0e-56) | Large GWAS |
| rs11575839 | NCR3 | GWAS association (p=1.0e-54) | Large GWAS |
| rs379464 | — | GWAS association (p=3.0e-52) | Large GWAS |
| rs1052693 | GTF2H4 | GWAS association (p=3.0e-48) | Large GWAS |
| rs7769158 | — | GWAS association (p=4.0e-47) | Large GWAS |
| rs148783236 | USP8 | GWAS association (p=5.0e-40) | Large GWAS |
| rs12198399 | — | GWAS association (p=1.0e-39) | Large GWAS |
| rs205002 | — | GWAS association (p=2.0e-35) | Large GWAS |
| rs1059362 | HLA-DRB1 | GWAS association (p=7.0e-35) | Large GWAS |
| rs2647074 | — | GWAS association (p=1.0e-34) | Large GWAS |
| rs34363414 | — | GWAS association (p=1.0e-33) | Large GWAS |
| rs74661798 | — | GWAS association (p=1.0e-32) | Large GWAS |
| rs200930495 | HLA-DQA1 | GWAS association (p=5.0e-31) | Large GWAS |
| rs1009382 | TNXB | GWAS association (p=5.0e-31) | Large GWAS |
| rs144515162 | — | GWAS association (p=1.0e-30) | Large GWAS |
| rs6459 | CYP21A2 | GWAS association (p=8.0e-30) | Large GWAS |
| rs114989909 | TNXB | GWAS association (p=8.0e-28) | Large GWAS |
| rs570636990 | — | GWAS association (p=4.0e-27) | Large GWAS |
| rs16869834 | NOTCH4 | GWAS association (p=5.0e-27) | Large GWAS |
| rs369969867 | — | GWAS association (p=1.0e-26) | Large GWAS |
| rs541803504 | — | GWAS association (p=4.0e-26) | Large GWAS |
| rs9501618 | TSBP1 | GWAS association (p=9.0e-26) | Large GWAS |
| rs114604222 | HLA-DRB5 | GWAS association (p=2.0e-25) | Large GWAS |
| rs59142330 | — | GWAS association (p=6.0e-24) | Large GWAS |
| rs3819290 | HLA-B | GWAS association (p=1.0e-23) | Large GWAS |
| rs9469220 | — | GWAS association (p=3.0e-23) | Large GWAS |
| rs28752520 | — | GWAS association (p=4.0e-23) | Large GWAS |
| rs3887381 | — | GWAS association (p=6.0e-23) | Large GWAS |
| rs2857009 | TNXB | GWAS association (p=1.0e-22) | Large GWAS |
| rs9276606 | — | GWAS association (p=3.0e-22) | Large GWAS |
| rs9271401 | — | GWAS association (p=9.0e-21) | Large GWAS |
| rs113399573 | HLA-DRB1 | GWAS association (p=1.0e-20) | Large GWAS |
| rs9268402 | TSBP1 | GWAS association (p=1.0e-20) | Large GWAS |
| rs9274664 | — | GWAS association (p=2.0e-20) | Large GWAS |
| rs28764720 | LOC105375010 | GWAS association (p=2.0e-20) | Large GWAS |
| rs9268896 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs11064501 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs9270637 | — | GWAS association (p=9.0e-20) | Large GWAS |
| rs9275160 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs1003879 | — | GWAS association (p=4.0e-19) | Large GWAS |
| rs9271762 | — | GWAS association (p=9.0e-18) | Large GWAS |
| rs113534515 | — | GWAS association (p=4.0e-17) | Large GWAS |
| rs115042889 | HLA-C | GWAS association (p=4.0e-16) | Large GWAS |
| rs4576281 | TSBP1 | GWAS association (p=5.0e-16) | Large GWAS |
| rs28755358 | — | GWAS association (p=8.0e-16) | Large GWAS |
| rs17207895 | TNXB | GWAS association (p=2.0e-15) | Large GWAS |
| rs28755170 | HLA-DQA1 | GWAS association (p=4.0e-15) | Large GWAS |
| rs28366255 | HLA-DRB1 | GWAS association (p=1.0e-14) | Large GWAS |
| rs9267898 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs3094187 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs9274903 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs206018 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs191018606 | HLA-DRB5 | GWAS association (p=5.0e-14) | Large GWAS |
| rs9468851 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs2844503 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs150243229 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs9274890 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs685244 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs9281391 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs180742749 | EHMT2 | GWAS association (p=2.0e-12) | Large GWAS |
| rs72850156 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs116180191 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs3104410 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs116738289 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs28929474 | SERPINA1 | GWAS association (p=2.0e-11) | Large GWAS |
| rs1404006 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs17020983 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs3135353 | — | GWAS association (p=5.0e-35) | Large GWAS |
| rs9267822 | NOTCH4 | GWAS association (p=6.0e-17) | Large GWAS |
| rs805285 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs17208153 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs2280774 | SKIC2 | GWAS association (p=8.0e-29) | Small GWAS |
Showing the top 100 of 101 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.