Trait
SNPs associated with cholesterol to total lipids in large LDL percentage
163 genetic variants across 64 genes have been associated with cholesterol to total lipids in large LDL percentage in published research. Key genes include ABCA1, ABCG8, AFF1.
Associated variants163 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs183130 | CETP | GWAS association (p=0.0e+00) | Large GWAS |
| rs1065853 | — | GWAS association (p=0.0e+00) | Large GWAS |
| rs7177289 | — | GWAS association (p=0.0e+00) | Large GWAS |
| rs429358 | APOE | GWAS association (p=5.0e-268) | Large GWAS |
| rs964184 | APOA5 | GWAS association (p=8.0e-268) | Large GWAS |
| rs102275 | TMEM258 | GWAS association (p=9.0e-264) | Large GWAS |
| rs115849089 | — | GWAS association (p=9.0e-205) | Large GWAS |
| rs118147862 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs7254892 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs112180569 | — | GWAS association (p=2.0e-142) | Large GWAS |
| rs2980888 | — | GWAS association (p=1.0e-122) | Large GWAS |
| rs1260326 | GCKR | GWAS association (p=3.0e-97) | Large GWAS |
| rs12740374 | CELSR2 | GWAS association (p=3.0e-94) | Large GWAS |
| rs3764261 | — | GWAS association (p=1.0e-93) | Large GWAS |
| rs1532085 | — | GWAS association (p=6.0e-87) | Large GWAS |
| rs139974673 | — | GWAS association (p=3.0e-82) | Large GWAS |
| rs9987289 | LOC157273 | GWAS association (p=1.0e-74) | Large GWAS |
| rs597808 | ATXN2 | GWAS association (p=1.0e-64) | Large GWAS |
| rs1800961 | HNF4A | GWAS association (p=3.0e-64) | Large GWAS |
| rs174580 | FADS2 | GWAS association (p=8.0e-62) | Large GWAS |
| rs2070895 | LIPC | GWAS association (p=4.0e-59) | Large GWAS |
| rs5744552 | POLK | GWAS association (p=7.0e-58) | Large GWAS |
| rs35493868 | — | GWAS association (p=5.0e-54) | Large GWAS |
| rs71353892 | — | GWAS association (p=6.0e-53) | Large GWAS |
| rs1154988 | — | GWAS association (p=1.0e-50) | Large GWAS |
| rs117026536 | LPL | GWAS association (p=9.0e-46) | Large GWAS |
| rs200561116 | — | GWAS association (p=5.0e-44) | Large GWAS |
| rs3768321 | — | GWAS association (p=2.0e-43) | Large GWAS |
| rs2066718 | ABCA1 | GWAS association (p=9.0e-41) | Large GWAS |
| rs72836561 | — | GWAS association (p=5.0e-40) | Large GWAS |
| rs191555775 | LPA | GWAS association (p=2.0e-38) | Large GWAS |
| rs6073958 | — | GWAS association (p=4.0e-37) | Large GWAS |
| rs3775228 | — | GWAS association (p=8.0e-34) | Large GWAS |
| rs78058190 | — | GWAS association (p=1.0e-33) | Large GWAS |
| rs367070 | — | GWAS association (p=2.0e-33) | Large GWAS |
| rs1367117 | APOB | GWAS association (p=5.0e-33) | Large GWAS |
| rs77265569 | — | GWAS association (p=3.0e-32) | Large GWAS |
| rs13107325 | SLC39A8 | GWAS association (p=3.0e-31) | Large GWAS |
| rs168622 | — | GWAS association (p=3.0e-31) | Large GWAS |
| rs7924036 | — | GWAS association (p=7.0e-31) | Large GWAS |
| rs199978239 | — | GWAS association (p=8.0e-30) | Large GWAS |
| rs465002 | C5orf67 | GWAS association (p=3.0e-29) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=4.0e-28) | Large GWAS |
| rs13235365 | — | GWAS association (p=6.0e-28) | Large GWAS |
| rs13389219 | COBLL1 | GWAS association (p=1.0e-27) | Large GWAS |
| rs4245791 | ABCG8 | GWAS association (p=5.0e-27) | Large GWAS |
| rs4969142 | PGS1 | GWAS association (p=1.0e-26) | Large GWAS |
| rs199900492 | — | GWAS association (p=8.0e-26) | Large GWAS |
| rs4871603 | — | GWAS association (p=3.0e-25) | Large GWAS |
| rs11075253 | PDXDC1 | GWAS association (p=8.0e-25) | Large GWAS |
| rs10647753 | — | GWAS association (p=8.0e-25) | Large GWAS |
| rs635769 | — | GWAS association (p=1.0e-24) | Large GWAS |
| rs147711004 | — | GWAS association (p=3.0e-24) | Large GWAS |
| rs998584 | POLR1C | GWAS association (p=6.0e-24) | Large GWAS |
| rs2068888 | — | GWAS association (p=7.0e-24) | Large GWAS |
| rs73455626 | — | GWAS association (p=2.0e-22) | Large GWAS |
| rs4722551 | LOC105375199 | GWAS association (p=3.0e-22) | Large GWAS |
| rs147233090 | — | GWAS association (p=5.0e-22) | Large GWAS |
| rs1165287 | PCSK9 | GWAS association (p=2.0e-21) | Large GWAS |
| rs3767962 | DR1 | GWAS association (p=4.0e-21) | Large GWAS |
| rs781006834 | — | GWAS association (p=5.0e-21) | Large GWAS |
| rs2229738 | CPT1A | GWAS association (p=6.0e-21) | Large GWAS |
| rs117760119 | — | GWAS association (p=1.0e-20) | Large GWAS |
| rs2494748 | AKT1 | GWAS association (p=2.0e-20) | Large GWAS |
| rs140779352 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs72749126 | C9orf64 | GWAS association (p=4.0e-19) | Large GWAS |
| rs903502 | PGAP3 | GWAS association (p=1.0e-18) | Large GWAS |
| rs2281719 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs7703282 | ANKDD1B | GWAS association (p=4.0e-18) | Large GWAS |
| rs9844972 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs2487294 | — | GWAS association (p=3.0e-17) | Large GWAS |
| rs77960347 | LIPG | GWAS association (p=3.0e-17) | Large GWAS |
| rs140628616 | — | GWAS association (p=4.0e-17) | Large GWAS |
| rs10750766 | — | GWAS association (p=4.0e-17) | Large GWAS |
| rs13044413 | — | GWAS association (p=5.0e-17) | Large GWAS |
| rs11030105 | BDNF | GWAS association (p=8.0e-17) | Large GWAS |
| rs5398 | SLC2A2 | GWAS association (p=1.0e-16) | Large GWAS |
| rs10773049 | ZNF664-RFLNA | GWAS association (p=3.0e-16) | Large GWAS |
| rs11751347 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs71468663 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs576111528 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs746764957 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs2263329 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs2729804 | — | GWAS association (p=5.0e-15) | Large GWAS |
| rs17145750 | MLXIPL | GWAS association (p=6.0e-15) | Large GWAS |
| rs6800707 | NISCH | GWAS association (p=7.0e-15) | Large GWAS |
| rs62102718 | — | GWAS association (p=9.0e-15) | Large GWAS |
| rs35104374 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs7704457 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs10410204 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs55820219 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs771193934 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs4299376 | ABCG8 | GWAS association (p=5.0e-14) | Large GWAS |
| rs4820323 | MAFF | GWAS association (p=7.0e-14) | Large GWAS |
| rs603424 | PKD2L1 | GWAS association (p=1.0e-13) | Large GWAS |
| rs9266834 | MICA | GWAS association (p=1.0e-13) | Large GWAS |
| rs13284054 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs35246381 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs144835520 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs35913552 | — | GWAS association (p=3.0e-13) | Large GWAS |
Showing the top 100 of 163 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.