Trait
SNPs associated with Angina pectoris
149 genetic variants across 50 genes have been associated with Angina pectoris in published research. Key genes include ADAMTS7, ALDH2, APOA5.
Associated variants149 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs10757274 | CDKN2B-AS1 | Higher risk of angina pectoris | Meta-analysis |
| rs1537371 | CDKN2B-AS1 | GWAS association (p=5.0e-101) | Major Consortium Study |
| rs10455872 | LPA | GWAS association (p=2.0e-90) | Major Consortium Study |
| rs12740374 | CELSR2 | GWAS association (p=4.0e-30) | Major Consortium Study |
| rs9980618 | — | GWAS association (p=1.0e-21) | Major Consortium Study |
| rs9515203 | COL4A2 | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs56179563 | — | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs7500448 | — | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs4888372 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs7176070 | — | GWAS association (p=8.0e-12) | Major Consortium Study |
| rs964184 | APOA5 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs12473819 | GGCX | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs3208305 | LPL | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs79633844 | ICA1L | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs12190287 | TCF21 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs9349379 | PHACTR1 | GWAS association (p=3.0e-30) | Major Consortium Study |
| rs28451064 | — | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs55730499 | LPA | GWAS association (p=6.0e-52) | Large GWAS |
| rs4007642 | CDKN2B-AS1 | GWAS association (p=7.0e-47) | Large GWAS |
| rs74617384 | — | GWAS association (p=2.0e-33) | Large GWAS |
| rs56393506 | — | GWAS association (p=2.0e-29) | Large GWAS |
| rs646776 | CELSR2 | GWAS association (p=5.0e-28) | Large GWAS |
| rs149299884 | — | GWAS association (p=9.0e-26) | Large GWAS |
| rs671 | ALDH2 | GWAS association (p=4.0e-24) | Large GWAS |
| rs10811654 | CDKN2B-AS1 | GWAS association (p=8.0e-24) | Large GWAS |
| rs660240 | CELSR2 | GWAS association (p=7.0e-23) | Large GWAS |
| rs11066132 | NAA25 | GWAS association (p=4.0e-22) | Large GWAS |
| rs140570886 | — | GWAS association (p=3.0e-21) | Large GWAS |
| rs10305838 | EDNRA | GWAS association (p=2.0e-20) | Large GWAS |
| rs2327429 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs2128739 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs13306206 | APOB | GWAS association (p=5.0e-19) | Large GWAS |
| rs12324886 | ADAMTS7 | GWAS association (p=2.0e-18) | Large GWAS |
| rs72664318 | PLPP3 | GWAS association (p=1.0e-17) | Large GWAS |
| rs10700825 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs8037001 | — | GWAS association (p=3.0e-17) | Large GWAS |
| rs11072799 | — | GWAS association (p=7.0e-17) | Large GWAS |
| rs7182131 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs1894401 | FES | GWAS association (p=1.0e-16) | Large GWAS |
| rs429358 | APOE | GWAS association (p=1.0e-16) | Large GWAS |
| rs1909196 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs1065853 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs7412 | APOE | GWAS association (p=7.0e-16) | Large GWAS |
| rs2028900 | MAT2A | GWAS association (p=4.0e-15) | Large GWAS |
| rs2378584 | MIA3 | GWAS association (p=2.0e-14) | Large GWAS |
| rs7183988 | FES | GWAS association (p=2.0e-14) | Large GWAS |
| rs3129987 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs17114036 | PLPP3 | GWAS association (p=6.0e-14) | Large GWAS |
| rs7161774 | — | GWAS association (p=9.0e-14) | Large GWAS |
| rs149856401 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs11191593 | NT5C2 | GWAS association (p=3.0e-13) | Large GWAS |
| rs78049276 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs77346308 | FAM222A | GWAS association (p=3.0e-12) | Large GWAS |
| rs2523653 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs1837843 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs61904693 | — | GWAS association (p=6.0e-12) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=6.0e-12) | Large GWAS |
| rs72689147 | GUCY1A1 | GWAS association (p=7.0e-12) | Large GWAS |
| rs4932463 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs1870635 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs12907753 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs3130283 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs2165556 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs58721068 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs12705390 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs13031230 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs1384705 | — | GWAS association (p=9.0e-11) | Large GWAS |
| rs35058456 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs7681920 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs2306556 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs7528419 | CELSR2 | GWAS association (p=2.0e-10) | Large GWAS |
| rs1893250 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs4409766 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs2839812 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs12133641 | IL6R | GWAS association (p=3.0e-10) | Large GWAS |
| rs4667725 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs75041078 | — | GWAS association (p=6.0e-10) | Large GWAS |
| rs16986953 | — | GWAS association (p=6.0e-10) | Large GWAS |
| rs4146810 | CFDP1 | GWAS association (p=7.0e-10) | Large GWAS |
| rs12928974 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs28687065 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs111161432 | UNC5C | GWAS association (p=1.0e-09) | Large GWAS |
| rs1078004 | MAT2A | GWAS association (p=2.0e-09) | Large GWAS |
| rs1926032 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs7195324 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs45610632 | BRWD3 | GWAS association (p=2.0e-09) | Large GWAS |
| rs7873013 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs6841473 | EDNRA | GWAS association (p=3.0e-09) | Large GWAS |
| rs5975695 | FHL1 | GWAS association (p=3.0e-09) | Large GWAS |
| rs223288 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs111876722 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs62605615 | BRWD3 | GWAS association (p=4.0e-09) | Large GWAS |
| rs11226029 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs34273235 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs4675310 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs16998073 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs150430137 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs1443120 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs2738464 | LDLR | GWAS association (p=6.0e-09) | Large GWAS |
| rs13376155 | — | GWAS association (p=6.0e-09) | Large GWAS |
Showing the top 100 of 149 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.