Trait
SNPs associated with drug use measurement, Hypercholesterolemia
61 genetic variants across 29 genes have been associated with drug use measurement, Hypercholesterolemia in published research. Key genes include ABCA5, ABCG8, ABO.
Associated variants61 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12740374 | CELSR2 | GWAS association (p=6.0e-297) | Major Consortium Study |
| rs7528419 | CELSR2 | GWAS association (p=1.0e-248) | Major Consortium Study |
| rs12151108 | — | GWAS association (p=1.0e-220) | Major Consortium Study |
| rs61194703 | — | GWAS association (p=4.0e-193) | Major Consortium Study |
| rs28601761 | — | GWAS association (p=3.0e-137) | Major Consortium Study |
| rs2954017 | — | GWAS association (p=4.0e-83) | Major Consortium Study |
| rs28362286 | PCSK9 | GWAS association (p=7.0e-48) | Major Consortium Study |
| rs142130958 | — | GWAS association (p=5.0e-43) | Major Consortium Study |
| rs35529421 | DOCK7 | GWAS association (p=8.0e-39) | Major Consortium Study |
| rs636523 | DOCK7 | GWAS association (p=3.0e-34) | Major Consortium Study |
| rs484084 | — | GWAS association (p=1.0e-25) | Major Consortium Study |
| rs4860951 | — | GWAS association (p=3.0e-24) | Major Consortium Study |
| rs12149832 | FTO | GWAS association (p=5.0e-24) | Major Consortium Study |
| rs7903146 | TCF7L2 | GWAS association (p=1.0e-22) | Major Consortium Study |
| rs35198068 | — | GWAS association (p=4.0e-21) | Major Consortium Study |
| rs6882076 | TIMD4 | GWAS association (p=7.0e-21) | Major Consortium Study |
| rs17725246 | — | GWAS association (p=4.0e-19) | Major Consortium Study |
| rs10049758 | — | GWAS association (p=8.0e-19) | Major Consortium Study |
| rs556107 | — | GWAS association (p=4.0e-18) | Major Consortium Study |
| rs2043082 | — | GWAS association (p=5.0e-17) | Major Consortium Study |
| rs56137030 | FTO | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs15285 | LPL | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs13108218 | — | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs3741298 | ZPR1 | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs1712248 | — | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs2673142 | — | GWAS association (p=2.0e-15) | Major Consortium Study |
| rs188743906 | — | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs5471 | HP | GWAS association (p=7.0e-15) | Major Consortium Study |
| rs2126264 | — | GWAS association (p=6.0e-14) | Major Consortium Study |
| rs563290 | — | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs12464355 | INSIG2 | GWAS association (p=5.0e-13) | Major Consortium Study |
| rs2169387 | — | GWAS association (p=6.0e-13) | Major Consortium Study |
| rs1055129 | TRIM47 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs1169288 | HNF1A | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs4560319 | PXK | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs4921913 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs4485425 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs41279633 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs2138157 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs56130071 | DNAH11 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs73015020 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs4299376 | ABCG8 | GWAS association (p=5.0e-53) | Major Consortium Study |
| rs12916 | HMGCR | GWAS association (p=6.0e-39) | Major Consortium Study |
| rs6689 | HLA-DQB1 | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs6905288 | POLR1C | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs1331309 | — | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs10455872 | LPA | GWAS association (p=2.0e-85) | Major Consortium Study |
| rs9297994 | — | GWAS association (p=5.0e-20) | Major Consortium Study |
| rs115478735 | ABO | GWAS association (p=3.0e-60) | Major Consortium Study |
| rs174549 | FADS1 | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs964184 | APOA5 | GWAS association (p=2.0e-103) | Major Consortium Study |
| rs76970536 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs10846744 | SCARB1 | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs2000999 | HPR | GWAS association (p=2.0e-40) | Major Consortium Study |
| rs573431210 | ABCA5 | GWAS association (p=6.0e-15) | Major Consortium Study |
| rs58542926 | TM6SF2 | GWAS association (p=7.0e-96) | Major Consortium Study |
| rs7412 | APOE | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs1883711 | — | GWAS association (p=2.0e-30) | Major Consortium Study |
| rs11591147 | PCSK9 | GWAS association (p=2.0e-127) | Major Consortium Study |
| rs668948 | LOC124905593 | GWAS association (p=3.0e-125) | Major Consortium Study |
| rs1260326 | GCKR | GWAS association (p=1.0e-49) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.