Trait
SNPs associated with Kidney Failure
44 genetic variants across 19 genes have been associated with Kidney Failure in published research. Key genes include APOL1, CPS1, CYP1A1.
Associated variants44 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs28362063 | UMOD | GWAS association (p=4.0e-145) | Major Consortium Study |
| rs73728279 | — | GWAS association (p=6.0e-42) | Major Consortium Study |
| rs10224210 | — | GWAS association (p=4.0e-40) | Major Consortium Study |
| rs7903146 | TCF7L2 | GWAS association (p=8.0e-29) | Major Consortium Study |
| rs34872471 | TCF7L2 | GWAS association (p=5.0e-28) | Major Consortium Study |
| rs2486272 | GATM | GWAS association (p=8.0e-26) | Major Consortium Study |
| rs2467865 | — | GWAS association (p=1.0e-25) | Major Consortium Study |
| rs80025274 | WDR72 | GWAS association (p=7.0e-21) | Major Consortium Study |
| rs17730281 | WDR72 | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs4269133 | — | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs8026743 | LOC105370777 | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs11642015 | FTO | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs399277 | TPPP | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs8036349 | — | GWAS association (p=7.0e-16) | Major Consortium Study |
| rs3127579 | SLC22A2 | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs13125101 | LOC124900725 | GWAS association (p=4.0e-15) | Major Consortium Study |
| rs948493 | — | GWAS association (p=6.0e-15) | Major Consortium Study |
| rs2622821 | — | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs149708592 | — | GWAS association (p=5.0e-14) | Major Consortium Study |
| rs72681869 | SOS2 | GWAS association (p=6.0e-14) | Major Consortium Study |
| rs11099098 | LOC124900725 | GWAS association (p=6.0e-14) | Major Consortium Study |
| rs4690780 | USP38 | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs17413465 | — | GWAS association (p=5.0e-13) | Major Consortium Study |
| rs466059 | TPPP | GWAS association (p=6.0e-13) | Major Consortium Study |
| rs28640218 | UMOD | GWAS association (p=8.0e-13) | Major Consortium Study |
| rs16998073 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs3119311 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs4320917 | NR1H3 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs434215 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs8025766 | LOC105370777 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs2472297 | CYP1A1 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs8705 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs13225723 | LINC02577 | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs3925584 | LOC101928338 | GWAS association (p=6.0e-37) | Major Consortium Study |
| rs6464165 | PRKAG2 | GWAS association (p=1.0e-53) | Major Consortium Study |
| rs8096658 | — | GWAS association (p=5.0e-14) | Major Consortium Study |
| rs334 | HBB | GWAS association (p=4.0e-25) | Major Consortium Study |
| rs60910145 | APOL1 | GWAS association (p=3.0e-26) | Major Consortium Study |
| rs7742789 | — | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs73885319 | APOL1 | GWAS association (p=2.0e-23) | Major Consortium Study |
| rs1047891 | CPS1 | GWAS association (p=2.0e-15) | Major Consortium Study |
| rs77924615 | — | GWAS association (p=5.0e-120) | Major Consortium Study |
| rs62048402 | FTO | GWAS association (p=5.0e-19) | Major Consortium Study |
| rs28910285 | — | GWAS association (p=9.0e-17) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.