Trait
SNPs associated with total lipids in LDL measurement
90 genetic variants across 27 genes have been associated with total lipids in LDL measurement in published research. Key genes include ABCA6, ABCG5, ABCG8.
Associated variants90 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs429358 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs7412 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs12151108 | — | GWAS association (p=2.0e-250) | Large GWAS |
| rs12740374 | CELSR2 | GWAS association (p=4.0e-205) | Large GWAS |
| rs118147862 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs7254892 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs562338 | — | GWAS association (p=3.0e-184) | Large GWAS |
| rs28601761 | — | GWAS association (p=2.0e-77) | Large GWAS |
| rs58542926 | TM6SF2 | GWAS association (p=1.0e-75) | Large GWAS |
| rs102275 | TMEM258 | GWAS association (p=1.0e-73) | Large GWAS |
| rs3846662 | HMGCR | GWAS association (p=3.0e-72) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=3.0e-64) | Large GWAS |
| rs964184 | APOA5 | GWAS association (p=2.0e-58) | Large GWAS |
| rs1260326 | GCKR | GWAS association (p=2.0e-57) | Large GWAS |
| rs12750160 | USP24 | GWAS association (p=2.0e-46) | Large GWAS |
| rs6073958 | — | GWAS association (p=1.0e-43) | Large GWAS |
| rs11887534 | ABCG5 | GWAS association (p=1.0e-39) | Large GWAS |
| rs7137828 | ATXN2 | GWAS association (p=5.0e-38) | Large GWAS |
| rs2519093 | ABO | GWAS association (p=1.0e-37) | Large GWAS |
| rs112875651 | — | GWAS association (p=2.0e-37) | Large GWAS |
| rs11751024 | — | GWAS association (p=1.0e-36) | Large GWAS |
| rs1168127 | DOCK7 | GWAS association (p=3.0e-32) | Large GWAS |
| rs557933 | — | GWAS association (p=4.0e-30) | Large GWAS |
| rs12916 | HMGCR | GWAS association (p=1.0e-29) | Large GWAS |
| rs147711004 | — | GWAS association (p=2.0e-28) | Large GWAS |
| rs6938647 | — | GWAS association (p=2.0e-28) | Large GWAS |
| rs56325564 | — | GWAS association (p=9.0e-28) | Large GWAS |
| rs118170342 | — | GWAS association (p=2.0e-26) | Large GWAS |
| rs115478735 | ABO | GWAS association (p=2.0e-25) | Large GWAS |
| rs35980001 | — | GWAS association (p=3.0e-25) | Large GWAS |
| rs58198139 | — | GWAS association (p=4.0e-25) | Large GWAS |
| rs6475606 | CDKN2B-AS1 | GWAS association (p=6.0e-25) | Large GWAS |
| rs9987289 | LOC157273 | GWAS association (p=1.0e-23) | Large GWAS |
| rs4307732 | — | GWAS association (p=1.0e-23) | Large GWAS |
| rs34596921 | — | GWAS association (p=1.0e-22) | Large GWAS |
| rs780094 | GCKR | GWAS association (p=2.0e-22) | Large GWAS |
| rs2866372 | — | GWAS association (p=6.0e-21) | Large GWAS |
| rs4299376 | ABCG8 | GWAS association (p=2.0e-20) | Large GWAS |
| rs28745910 | — | GWAS association (p=1.0e-17) | Large GWAS |
| rs150169808 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs55714927 | — | GWAS association (p=3.0e-17) | Large GWAS |
| rs1458038 | LOC124900725 | GWAS association (p=3.0e-17) | Large GWAS |
| rs1800961 | HNF4A | GWAS association (p=6.0e-17) | Large GWAS |
| rs35081008 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs2081687 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs11621792 | — | GWAS association (p=8.0e-16) | Large GWAS |
| rs771193934 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs6882345 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs34042070 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs13108218 | — | GWAS association (p=5.0e-15) | Large GWAS |
| rs116734477 | ITGA1 | GWAS association (p=6.0e-15) | Large GWAS |
| rs1461729 | LOC157273 | GWAS association (p=1.0e-14) | Large GWAS |
| rs1883711 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs7734476 | CSNK1G3 | GWAS association (p=2.0e-14) | Large GWAS |
| rs525028 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs77542162 | ABCA6 | GWAS association (p=3.0e-14) | Large GWAS |
| rs74617384 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs2740488 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs59379014 | ST3GAL4 | GWAS association (p=6.0e-14) | Large GWAS |
| rs9604463 | GAS6 | GWAS association (p=3.0e-13) | Large GWAS |
| rs12948394 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs201383809 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs34071855 | — | GWAS association (p=4.0e-13) | Large GWAS |
| rs11693150 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs9884390 | — | GWAS association (p=7.0e-13) | Large GWAS |
| rs55994889 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs11636952 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs115740542 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs11755689 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs140798831 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs111278137 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs514230 | LINC01132 | GWAS association (p=6.0e-12) | Large GWAS |
| rs8191852 | IGF2R | GWAS association (p=7.0e-12) | Large GWAS |
| rs12150378 | — | GWAS association (p=7.0e-12) | Large GWAS |
| rs76428106 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs11206517 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs7177289 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs6920309 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs2624847 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs472495 | PCSK9 | GWAS association (p=4.0e-11) | Large GWAS |
| rs12046182 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs73013176 | SMARCA4 | GWAS association (p=9.0e-11) | Large GWAS |
| rs2427531 | ZGPAT | GWAS association (p=9.0e-11) | Large GWAS |
| rs41279633 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs10832963 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs4810479 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs6734238 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs1499279 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs5817082 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs200210321 | — | GWAS association (p=2.0e-63) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.