Trait

SNPs associated with Alcohol use disorder

102 genetic variants across 31 genes have been associated with Alcohol use disorder in published research. Key genes include ADH1B, ALDH2, ARHGAP15.

Associated variants102 total

rsidGeneEffectEvidence
rs13135092—GWAS association (p=2.0e-31)Meta-analysis
rs11733695—GWAS association (p=3.0e-30)Meta-analysis
rs146788033—GWAS association (p=1.0e-25)Meta-analysis
rs13107325SLC39A8GWAS association (p=8.0e-23)Meta-analysis
rs144198753LOC105377343GWAS association (p=2.0e-22)Meta-analysis
rs11940694KLBGWAS association (p=7.0e-21)Meta-analysis
rs1260326GCKRGWAS association (p=1.0e-20)Meta-analysis
rs11336847—GWAS association (p=5.0e-16)Meta-analysis
rs138084129—GWAS association (p=5.0e-15)Meta-analysis
rs2141284—GWAS association (p=5.0e-14)Meta-analysis
rs9926289FTOGWAS association (p=7.0e-13)Meta-analysis
rs3114045—GWAS association (p=7.0e-13)Meta-analysis
rs6589386—GWAS association (p=7.0e-12)Meta-analysis
rs142151894—GWAS association (p=3.0e-11)Meta-analysis
rs9937709FTOGWAS association (p=4.0e-11)Meta-analysis
rs10717830—GWAS association (p=1.0e-10)Meta-analysis
rs56722963—GWAS association (p=2.0e-10)Meta-analysis
rs6421482PDE4BGWAS association (p=3.0e-10)Meta-analysis
rs7693958—GWAS association (p=5.0e-10)Meta-analysis
rs62062288MAPTGWAS association (p=5.0e-10)Meta-analysis
rs492602FUT2GWAS association (p=8.0e-10)Meta-analysis
rs11366076—GWAS association (p=1.0e-09)Meta-analysis
rs62250713—GWAS association (p=1.0e-09)Meta-analysis
rs10270358—GWAS association (p=2.0e-09)Meta-analysis
rs9679319—GWAS association (p=2.0e-09)Meta-analysis
rs13382553THSD7BGWAS association (p=2.0e-09)Meta-analysis
rs1783835—GWAS association (p=2.0e-09)Meta-analysis
rs4975012KLBGWAS association (p=3.0e-09)Meta-analysis
rs2673136—GWAS association (p=4.0e-09)Meta-analysis
rs12743648—GWAS association (p=5.0e-09)Meta-analysis
rs11463615—GWAS association (p=6.0e-09)Meta-analysis
rs4240624LOC157273GWAS association (p=6.0e-09)Meta-analysis
rs73403005SEMA6DGWAS association (p=6.0e-09)Meta-analysis
rs2293576SLC39A13GWAS association (p=6.0e-09)Meta-analysis
rs7073987—GWAS association (p=7.0e-09)Meta-analysis
rs140239378—GWAS association (p=7.0e-09)Meta-analysis
rs7117878—GWAS association (p=8.0e-09)Meta-analysis
rs2582405PENK-AS1GWAS association (p=9.0e-09)Meta-analysis
rs2602856LOC100507053GWAS association (p=1.0e-08)Meta-analysis
rs576859—GWAS association (p=1.0e-08)Meta-analysis
rs7078436—GWAS association (p=1.0e-08)Meta-analysis
rs2713557—GWAS association (p=2.0e-08)Meta-analysis
rs12192123MICB-DTGWAS association (p=2.0e-08)Meta-analysis
rs2533200DPP6GWAS association (p=2.0e-08)Meta-analysis
rs34806762—GWAS association (p=2.0e-08)Meta-analysis
rs72768626—GWAS association (p=2.0e-08)Meta-analysis
rs4953148—GWAS association (p=2.0e-08)Meta-analysis
rs1920650—GWAS association (p=2.0e-08)Meta-analysis
rs13411140ARHGAP15GWAS association (p=3.0e-08)Meta-analysis
rs35040843—GWAS association (p=3.0e-08)Meta-analysis
rs67672396—GWAS association (p=4.0e-08)Meta-analysis
rs61974485ARID4AGWAS association (p=4.0e-08)Meta-analysis
rs7900002—GWAS association (p=4.0e-08)Meta-analysis
rs12296477SLC4A8GWAS association (p=4.0e-08)Meta-analysis
rs188514326—GWAS association (p=4.0e-08)Meta-analysis
rs1799971OPRM1Altered alcohol dependence risk, population-dependent directionMeta-analysis
rs13129401—GWAS association (p=5.0e-19)Meta-analysis
rs1229984ADH1BGWAS association (p=7.0e-162)Meta-analysis
rs148382129H2AZ1-DTGWAS association (p=3.0e-23)Meta-analysis
rs61767420—GWAS association (p=1.0e-08)Meta-analysis
rs494904—GWAS association (p=2.0e-15)Meta-analysis
rs1402398—GWAS association (p=1.0e-12)Meta-analysis
rs8008020—GWAS association (p=1.0e-09)Meta-analysis
rs2066702ADH1BGWAS association (p=6.0e-32)Large GWAS
rs3216150—GWAS association (p=1.0e-28)Large GWAS
rs12532657—GWAS association (p=3.0e-26)Large GWAS
rs1693457—GWAS association (p=1.0e-21)Large GWAS
rs1421085FTOGWAS association (p=6.0e-17)Large GWAS
rs530568312—GWAS association (p=4.0e-15)Large GWAS
rs150627184—GWAS association (p=6.0e-14)Large GWAS
rs145441368—GWAS association (p=2.0e-11)Large GWAS
rs13135439—GWAS association (p=2.0e-11)Large GWAS
rs12572486—GWAS association (p=4.0e-11)Large GWAS
rs2093374—GWAS association (p=5.0e-11)Large GWAS
rs13130101—GWAS association (p=9.0e-11)Large GWAS
rs472140—GWAS association (p=2.0e-10)Large GWAS
rs7517355—GWAS association (p=2.0e-10)Large GWAS
rs518853—GWAS association (p=3.0e-10)Large GWAS
rs671ALDH2Increased alcohol use disorder riskLarge GWAS
rs7701111IL7RGWAS association (p=8.0e-10)Large GWAS
rs17245607LOC105371723GWAS association (p=2.0e-09)Large GWAS
rs2717005VRK2GWAS association (p=2.0e-09)Large GWAS
rs67580605—GWAS association (p=3.0e-09)Large GWAS
rs10235277—GWAS association (p=4.0e-09)Large GWAS
rs2016795—GWAS association (p=5.0e-09)Large GWAS
rs7831483LINC01414GWAS association (p=7.0e-09)Large GWAS
rs3828783—GWAS association (p=7.0e-09)Large GWAS
rs565298761LOC105378521GWAS association (p=1.0e-08)Large GWAS
rs397950087—GWAS association (p=1.0e-08)Large GWAS
rs4545438—GWAS association (p=2.0e-08)Large GWAS
rs8112983—GWAS association (p=2.0e-08)Large GWAS
rs7111957SPI1GWAS association (p=2.0e-08)Large GWAS
rs75438204—GWAS association (p=2.0e-08)Large GWAS
rs499188—GWAS association (p=3.0e-08)Large GWAS
rs7924485SPI1GWAS association (p=3.0e-08)Large GWAS
rs34517574—GWAS association (p=4.0e-08)Large GWAS
rs11681373ZNF804AGWAS association (p=4.0e-08)Large GWAS
rs138084484—GWAS association (p=4.0e-08)Large GWAS
rs73792114GRK4GWAS association (p=5.0e-08)Large GWAS
rs6589894—GWAS association (p=5.0e-08)Large GWAS

Showing the top 100 of 102 variants by evidence strength.

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.

Alcohol use disorder — SNPs & genetic associations — Gene Wizard