Trait
SNPs associated with Alcohol use disorder
102 genetic variants across 31 genes have been associated with Alcohol use disorder in published research. Key genes include ADH1B, ALDH2, ARHGAP15.
Associated variants102 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs13135092 | — | GWAS association (p=2.0e-31) | Meta-analysis |
| rs11733695 | — | GWAS association (p=3.0e-30) | Meta-analysis |
| rs146788033 | — | GWAS association (p=1.0e-25) | Meta-analysis |
| rs13107325 | SLC39A8 | GWAS association (p=8.0e-23) | Meta-analysis |
| rs144198753 | LOC105377343 | GWAS association (p=2.0e-22) | Meta-analysis |
| rs11940694 | KLB | GWAS association (p=7.0e-21) | Meta-analysis |
| rs1260326 | GCKR | GWAS association (p=1.0e-20) | Meta-analysis |
| rs11336847 | — | GWAS association (p=5.0e-16) | Meta-analysis |
| rs138084129 | — | GWAS association (p=5.0e-15) | Meta-analysis |
| rs2141284 | — | GWAS association (p=5.0e-14) | Meta-analysis |
| rs9926289 | FTO | GWAS association (p=7.0e-13) | Meta-analysis |
| rs3114045 | — | GWAS association (p=7.0e-13) | Meta-analysis |
| rs6589386 | — | GWAS association (p=7.0e-12) | Meta-analysis |
| rs142151894 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs9937709 | FTO | GWAS association (p=4.0e-11) | Meta-analysis |
| rs10717830 | — | GWAS association (p=1.0e-10) | Meta-analysis |
| rs56722963 | — | GWAS association (p=2.0e-10) | Meta-analysis |
| rs6421482 | PDE4B | GWAS association (p=3.0e-10) | Meta-analysis |
| rs7693958 | — | GWAS association (p=5.0e-10) | Meta-analysis |
| rs62062288 | MAPT | GWAS association (p=5.0e-10) | Meta-analysis |
| rs492602 | FUT2 | GWAS association (p=8.0e-10) | Meta-analysis |
| rs11366076 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs62250713 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs10270358 | — | GWAS association (p=2.0e-09) | Meta-analysis |
| rs9679319 | — | GWAS association (p=2.0e-09) | Meta-analysis |
| rs13382553 | THSD7B | GWAS association (p=2.0e-09) | Meta-analysis |
| rs1783835 | — | GWAS association (p=2.0e-09) | Meta-analysis |
| rs4975012 | KLB | GWAS association (p=3.0e-09) | Meta-analysis |
| rs2673136 | — | GWAS association (p=4.0e-09) | Meta-analysis |
| rs12743648 | — | GWAS association (p=5.0e-09) | Meta-analysis |
| rs11463615 | — | GWAS association (p=6.0e-09) | Meta-analysis |
| rs4240624 | LOC157273 | GWAS association (p=6.0e-09) | Meta-analysis |
| rs73403005 | SEMA6D | GWAS association (p=6.0e-09) | Meta-analysis |
| rs2293576 | SLC39A13 | GWAS association (p=6.0e-09) | Meta-analysis |
| rs7073987 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs140239378 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs7117878 | — | GWAS association (p=8.0e-09) | Meta-analysis |
| rs2582405 | PENK-AS1 | GWAS association (p=9.0e-09) | Meta-analysis |
| rs2602856 | LOC100507053 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs576859 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs7078436 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs2713557 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs12192123 | MICB-DT | GWAS association (p=2.0e-08) | Meta-analysis |
| rs2533200 | DPP6 | GWAS association (p=2.0e-08) | Meta-analysis |
| rs34806762 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs72768626 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs4953148 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs1920650 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs13411140 | ARHGAP15 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs35040843 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs67672396 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs61974485 | ARID4A | GWAS association (p=4.0e-08) | Meta-analysis |
| rs7900002 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs12296477 | SLC4A8 | GWAS association (p=4.0e-08) | Meta-analysis |
| rs188514326 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs1799971 | OPRM1 | Altered alcohol dependence risk, population-dependent direction | Meta-analysis |
| rs13129401 | — | GWAS association (p=5.0e-19) | Meta-analysis |
| rs1229984 | ADH1B | GWAS association (p=7.0e-162) | Meta-analysis |
| rs148382129 | H2AZ1-DT | GWAS association (p=3.0e-23) | Meta-analysis |
| rs61767420 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs494904 | — | GWAS association (p=2.0e-15) | Meta-analysis |
| rs1402398 | — | GWAS association (p=1.0e-12) | Meta-analysis |
| rs8008020 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs2066702 | ADH1B | GWAS association (p=6.0e-32) | Large GWAS |
| rs3216150 | — | GWAS association (p=1.0e-28) | Large GWAS |
| rs12532657 | — | GWAS association (p=3.0e-26) | Large GWAS |
| rs1693457 | — | GWAS association (p=1.0e-21) | Large GWAS |
| rs1421085 | FTO | GWAS association (p=6.0e-17) | Large GWAS |
| rs530568312 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs150627184 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs145441368 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs13135439 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs12572486 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs2093374 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs13130101 | — | GWAS association (p=9.0e-11) | Large GWAS |
| rs472140 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs7517355 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs518853 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs671 | ALDH2 | Increased alcohol use disorder risk | Large GWAS |
| rs7701111 | IL7R | GWAS association (p=8.0e-10) | Large GWAS |
| rs17245607 | LOC105371723 | GWAS association (p=2.0e-09) | Large GWAS |
| rs2717005 | VRK2 | GWAS association (p=2.0e-09) | Large GWAS |
| rs67580605 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs10235277 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs2016795 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs7831483 | LINC01414 | GWAS association (p=7.0e-09) | Large GWAS |
| rs3828783 | — | GWAS association (p=7.0e-09) | Large GWAS |
| rs565298761 | LOC105378521 | GWAS association (p=1.0e-08) | Large GWAS |
| rs397950087 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs4545438 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs8112983 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs7111957 | SPI1 | GWAS association (p=2.0e-08) | Large GWAS |
| rs75438204 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs499188 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs7924485 | SPI1 | GWAS association (p=3.0e-08) | Large GWAS |
| rs34517574 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs11681373 | ZNF804A | GWAS association (p=4.0e-08) | Large GWAS |
| rs138084484 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs73792114 | GRK4 | GWAS association (p=5.0e-08) | Large GWAS |
| rs6589894 | — | GWAS association (p=5.0e-08) | Large GWAS |
Showing the top 100 of 102 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.