Trait
SNPs associated with total cholesterol measurement, blood VLDL cholesterol amount, chylomicron amount
111 genetic variants across 36 genes have been associated with total cholesterol measurement, blood VLDL cholesterol amount, chylomicron amount in published research. Key genes include ABCA1, ACACB, AFF1.
Associated variants111 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs964184 | APOA5 | GWAS association (p=2.0e-292) | Large GWAS |
| rs10455872 | LPA | GWAS association (p=7.0e-207) | Large GWAS |
| rs328 | LPL | GWAS association (p=2.0e-188) | Large GWAS |
| rs1065853 | — | GWAS association (p=7.0e-130) | Large GWAS |
| rs115849089 | — | GWAS association (p=1.0e-116) | Large GWAS |
| rs1260326 | GCKR | GWAS association (p=2.0e-107) | Large GWAS |
| rs2678379 | APOB | GWAS association (p=3.0e-97) | Large GWAS |
| rs16891156 | — | GWAS association (p=2.0e-90) | Large GWAS |
| rs28601761 | — | GWAS association (p=4.0e-89) | Large GWAS |
| rs79439217 | — | GWAS association (p=1.0e-87) | Large GWAS |
| rs2954021 | — | GWAS association (p=3.0e-83) | Large GWAS |
| rs584007 | — | GWAS association (p=5.0e-81) | Large GWAS |
| rs34060476 | — | GWAS association (p=7.0e-80) | Large GWAS |
| rs1007205 | — | GWAS association (p=9.0e-67) | Large GWAS |
| rs174553 | FADS1 | GWAS association (p=7.0e-66) | Large GWAS |
| rs45611741 | APOA5 | GWAS association (p=3.0e-65) | Large GWAS |
| rs58542926 | TM6SF2 | GWAS association (p=1.0e-60) | Large GWAS |
| rs157594 | — | GWAS association (p=2.0e-60) | Large GWAS |
| rs116843064 | ANGPTL4 | GWAS association (p=2.0e-56) | Large GWAS |
| rs183130 | CETP | GWAS association (p=3.0e-54) | Large GWAS |
| rs555766713 | PCSK7 | GWAS association (p=3.0e-49) | Large GWAS |
| rs821840 | CETP | GWAS association (p=7.0e-42) | Large GWAS |
| rs4665710 | — | GWAS association (p=2.0e-39) | Large GWAS |
| rs8107974 | — | GWAS association (p=2.0e-38) | Large GWAS |
| rs13240065 | MLXIPL | GWAS association (p=5.0e-37) | Large GWAS |
| rs13389219 | COBLL1 | GWAS association (p=4.0e-35) | Large GWAS |
| rs147555597 | — | GWAS association (p=4.0e-32) | Large GWAS |
| rs138458033 | — | GWAS association (p=7.0e-29) | Large GWAS |
| rs139974673 | — | GWAS association (p=3.0e-27) | Large GWAS |
| rs11429307 | — | GWAS association (p=1.0e-26) | Large GWAS |
| rs112107114 | — | GWAS association (p=5.0e-26) | Large GWAS |
| rs59484402 | — | GWAS association (p=5.0e-25) | Large GWAS |
| rs72836561 | — | GWAS association (p=2.0e-24) | Large GWAS |
| rs10903343 | FDFT1 | GWAS association (p=1.0e-21) | Large GWAS |
| rs6999612 | — | GWAS association (p=1.0e-21) | Large GWAS |
| rs6874202 | — | GWAS association (p=2.0e-20) | Large GWAS |
| rs4704834 | — | GWAS association (p=4.0e-20) | Large GWAS |
| rs2943635 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs10761752 | JMJD1C | GWAS association (p=3.0e-19) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=3.0e-19) | Large GWAS |
| rs568533060 | — | GWAS association (p=4.0e-19) | Large GWAS |
| rs142231215 | LPA | GWAS association (p=6.0e-19) | Large GWAS |
| rs6601512 | — | GWAS association (p=8.0e-19) | Large GWAS |
| rs1801689 | APOH | GWAS association (p=2.0e-18) | Large GWAS |
| rs28718232 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs9687846 | — | GWAS association (p=3.0e-18) | Large GWAS |
| rs1471251 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs2980755 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs632057 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs1495741 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs11749783 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs684773 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs442177 | AFF1 | GWAS association (p=5.0e-16) | Large GWAS |
| rs10184004 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs181349205 | LOC105379311 | GWAS association (p=3.0e-15) | Large GWAS |
| rs1936806 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs13108218 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs12359135 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs56001710 | LOC105375199 | GWAS association (p=3.0e-13) | Large GWAS |
| rs79598313 | — | GWAS association (p=4.0e-13) | Large GWAS |
| rs76866386 | — | GWAS association (p=4.0e-13) | Large GWAS |
| rs35867424 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs4717804 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs2275647 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs2925979 | CMIP | GWAS association (p=2.0e-12) | Large GWAS |
| rs2523675 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs3758060 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs2138161 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs7140110 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs78058190 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs189866430 | MCUB | GWAS association (p=1.0e-11) | Large GWAS |
| rs11644601 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs13262031 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs174529 | MYRF | GWAS association (p=2.0e-11) | Large GWAS |
| rs4846923 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs147649176 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs998584 | POLR1C | GWAS association (p=4.0e-11) | Large GWAS |
| rs687339 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs2575876 | ABCA1 | GWAS association (p=4.0e-11) | Large GWAS |
| rs7337339 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs1883711 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs150856119 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs144177163 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs6971365 | LOC105375508 | GWAS association (p=7.0e-11) | Large GWAS |
| rs7133378 | — | GWAS association (p=8.0e-11) | Large GWAS |
| rs535286942 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs2122982 | R3HDM2 | GWAS association (p=2.0e-10) | Large GWAS |
| rs41279633 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs6445879 | DNAH12 | GWAS association (p=4.0e-10) | Large GWAS |
| rs9910747 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs62441903 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs1800588 | LIPC | GWAS association (p=6.0e-10) | Large GWAS |
| rs35169799 | PLCB3 | GWAS association (p=8.0e-10) | Large GWAS |
| rs187918276 | ANKRD17 | GWAS association (p=8.0e-10) | Large GWAS |
| rs368970058 | RAB11B-AS1 | GWAS association (p=1.0e-09) | Large GWAS |
| rs6073958 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs9492442 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs10096872 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs522110 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs149793040 | ACACB | GWAS association (p=3.0e-09) | Large GWAS |
Showing the top 100 of 111 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.