Trait
SNPs associated with Hyperlipidemia
81 genetic variants across 35 genes have been associated with Hyperlipidemia in published research. Key genes include ABCA1, ABCG8, ABO.
Associated variants81 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs7528419 | CELSR2 | GWAS association (p=8.0e-300) | Major Consortium Study |
| rs138294113 | — | GWAS association (p=3.0e-220) | Major Consortium Study |
| rs73015020 | — | GWAS association (p=1.0e-201) | Major Consortium Study |
| rs28601761 | — | GWAS association (p=2.0e-179) | Major Consortium Study |
| rs11591147 | PCSK9 | GWAS association (p=2.0e-159) | Major Consortium Study |
| rs668948 | LOC124905593 | GWAS association (p=1.0e-145) | Major Consortium Study |
| rs28362286 | PCSK9 | GWAS association (p=5.0e-102) | Major Consortium Study |
| rs10455872 | LPA | GWAS association (p=2.0e-100) | Major Consortium Study |
| rs142130958 | — | GWAS association (p=8.0e-99) | Major Consortium Study |
| rs4299376 | ABCG8 | GWAS association (p=4.0e-76) | Major Consortium Study |
| rs429358 | APOE | GWAS association (p=1.0e-69) | Major Consortium Study |
| rs12740374 | CELSR2 | GWAS association (p=8.0e-68) | Major Consortium Study |
| rs115478735 | ABO | GWAS association (p=1.0e-66) | Major Consortium Study |
| rs1260326 | GCKR | GWAS association (p=1.0e-54) | Major Consortium Study |
| rs12916 | HMGCR | GWAS association (p=1.0e-52) | Major Consortium Study |
| rs12151108 | — | GWAS association (p=5.0e-45) | Major Consortium Study |
| rs3208305 | LPL | GWAS association (p=5.0e-41) | Major Consortium Study |
| rs541041 | LOC124905593 | GWAS association (p=2.0e-39) | Major Consortium Study |
| rs544187825 | — | GWAS association (p=9.0e-39) | Major Consortium Study |
| rs4665972 | SNX17 | GWAS association (p=2.0e-34) | Major Consortium Study |
| rs58542926 | TM6SF2 | GWAS association (p=1.0e-32) | Major Consortium Study |
| rs60201663 | PMFBP1 | GWAS association (p=1.0e-31) | Major Consortium Study |
| rs75278536 | LPL | GWAS association (p=1.0e-29) | Major Consortium Study |
| rs56156922 | — | GWAS association (p=2.0e-29) | Major Consortium Study |
| rs1421085 | FTO | GWAS association (p=3.0e-29) | Major Consortium Study |
| rs6882076 | TIMD4 | GWAS association (p=1.0e-28) | Major Consortium Study |
| rs1065853 | — | GWAS association (p=4.0e-28) | Major Consortium Study |
| rs7903146 | TCF7L2 | GWAS association (p=3.0e-23) | Major Consortium Study |
| rs17725246 | — | GWAS association (p=4.0e-23) | Major Consortium Study |
| rs10846742 | — | GWAS association (p=5.0e-23) | Major Consortium Study |
| rs2575876 | ABCA1 | GWAS association (p=9.0e-23) | Major Consortium Study |
| rs247617 | — | GWAS association (p=1.0e-22) | Major Consortium Study |
| rs12239737 | DOCK7 | GWAS association (p=2.0e-22) | Major Consortium Study |
| rs2068888 | — | GWAS association (p=3.0e-22) | Major Consortium Study |
| rs1169288 | HNF1A | GWAS association (p=1.0e-21) | Major Consortium Study |
| rs6544713 | ABCG8 | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs6072336 | — | GWAS association (p=7.0e-21) | Major Consortium Study |
| rs6812826 | — | GWAS association (p=7.0e-20) | Major Consortium Study |
| rs3809770 | — | GWAS association (p=8.0e-20) | Major Consortium Study |
| rs514230 | LINC01132 | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs10846744 | SCARB1 | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs61194703 | — | GWAS association (p=3.0e-19) | Major Consortium Study |
| rs2176040 | — | GWAS association (p=7.0e-19) | Major Consortium Study |
| rs6982502 | — | GWAS association (p=8.0e-18) | Major Consortium Study |
| rs998584 | POLR1C | GWAS association (p=8.0e-18) | Major Consortium Study |
| rs740516 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs9389269 | LOC105378010 | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs12350739 | — | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs62466264 | — | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs1584063 | — | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs12464355 | INSIG2 | GWAS association (p=6.0e-16) | Major Consortium Study |
| rs7216664 | UNC13D | GWAS association (p=8.0e-16) | Major Consortium Study |
| rs1913657 | — | GWAS association (p=9.0e-16) | Major Consortium Study |
| rs10107182 | — | GWAS association (p=2.0e-15) | Major Consortium Study |
| rs6689 | HLA-DQB1 | GWAS association (p=2.0e-15) | Major Consortium Study |
| rs59950280 | — | GWAS association (p=4.0e-15) | Major Consortium Study |
| rs4418728 | — | GWAS association (p=4.0e-15) | Major Consortium Study |
| rs10184004 | — | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs77375493 | JAK2 | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs174549 | FADS1 | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs112771035 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs9747749 | GIP | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs13389219 | COBLL1 | GWAS association (p=7.0e-13) | Major Consortium Study |
| rs3936511 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs4921914 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs157934 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs8081954 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs35529421 | DOCK7 | GWAS association (p=8.0e-12) | Major Consortium Study |
| rs28498684 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs3755636 | PCCB | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs74181299 | CEP68 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs17476364 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs193159913 | BMPR2 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs4470903 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs964184 | APOA5 | GWAS association (p=1.0e-194) | Major Consortium Study |
| rs2126264 | — | GWAS association (p=4.0e-15) | Major Consortium Study |
| rs12239736 | — | GWAS association (p=2.0e-51) | Major Consortium Study |
| rs4245791 | ABCG8 | GWAS association (p=7.0e-63) | Major Consortium Study |
| rs563290 | — | GWAS association (p=1.0e-130) | Major Consortium Study |
| rs7412 | APOE | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs116843064 | ANGPTL4 | GWAS association (p=2.0e-15) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.